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Partially Hydrolyzed Guar Gum (PHGG) para Irritable Bowel Syndrome (IBS)

B

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

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B

Conclusão

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

Key Study Findings

Randomized Controlled Trial n=47 8 weeks Double-blind
Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and …
Dose: None vs: Placebo (Group I) and partial formulation (Group II) Outcome: IBS quality of life (QoL questionnaire) Efeito: Dysphoria: median diff -5 (Group III) vs -1 (contr 0.0021 (dysphoria Group III)

População: Patients with IBS

Controlled Clinical Trial
Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable …
Dose: Partially hydrolyzed guar gum (PHGG) vs: Drug therapy alone Outcome: Gut bacteria ratios and inflammatory markers Efeito: None None

População: Patients with IBD or IBS on drug therapy

Controlled Clinical Trial 12.9 weeks
Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel …
Dose: None vs: baseline Outcome: IBS symptom improvement Efeito: None None

População: Ibs undertook a 90-day intervention and follow-up

Case Reports
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Dose: None vs: None Outcome: None Efeito: None None

População: None

Randomized Controlled Trial 13.0 weeks Double-blind
Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: …
Dose: None vs: Placebo Outcome: Bowel function Efeito: None p=0.05

População: healthy volunteers

Randomized Controlled Trial 12 weeks
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients …
Dose: partially hydrolyzed guar gum (PHGG) 5g/day vs: placebo Outcome: IBS-SSS and bloating severity Efeito: significant improvement in overall IBS-SSS <0.05

População: Adults with IBS

Key Statistics

5

Estudos

350

Participantes

Positive

B

Nota

Referenced Papers

Journal of pediatric … 2016 19 citações
Minerva gastroenterologica e … 2013
Nutrition (Burbank, Los … 2003 143 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
5-7 g/day
ibssupport:
5 g/day for 4-12 weeks
siboadjunct:
5 g/day alongside antimicrobial therapy

Limite superior: Well-tolerated up to 36 g/day in clinical trials

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
None 8 weeks Positive 47
Partially hydrolyzed guar gum (PHGG) -- Positive --
None 12.9 weeks Positive --
None -- Positive --
None 13.0 weeks Mixed --
partially hydrolyzed guar gum (PHGG) 5g/day 12 weeks Positive --
various probiotic strains -- Mixed --
None 4.0 weeks Positive --

Melhor horário: Mixed into food or beverages; dissolves completely without altering texture

Safety & Side Effects

Efeitos Colaterais Relatados

  • Minimal gas and bloating (significantly less than other fibers)
  • Mild abdominal discomfort in rare cases
  • Loose stools at very high doses

Interações Conhecidas

  • May slow absorption of some medications (space 1-2 hours)
  • Diabetes medications (may modestly affect blood glucose)

Ingestão máxima tolerável: Well-tolerated up to 36 g/day in clinical trials

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Partially Hydrolyzed Guar Gum (PHGG) help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 350 participants, there is moderate evidence from clinical studies that Partially Hydrolyzed Guar Gum (PHGG) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Partially Hydrolyzed Guar Gum (PHGG) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 5-7 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Partially Hydrolyzed Guar Gum (PHGG)?
Reported side effects may include Minimal gas and bloating (significantly less than other fibers), Mild abdominal discomfort in rare cases, Loose stools at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Partially Hydrolyzed Guar Gum (PHGG) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Related Evidence

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.