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Aloe Vera (Inner Leaf Gel) para Irritable Bowel Syndrome (IBS)

C

Small RCTs show modest improvement in IBS symptoms. Conflicting results; some studies show no benefit over placebo.

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C

Conclusão

Small RCTs show modest improvement in IBS symptoms. Conflicting results; some studies show no benefit over placebo.

Key Study Findings

Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None vs: None Outcome: None Efeito: None None

População: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)

Review
Natural Products for the Treatment of Irritable Bowel Syndrome.
Dose: None vs: None Outcome: None Efeito: None None

População: Patients with irritable bowel syndrome

Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None vs: Various Outcome: IBS symptom improvement Efeito: Probiotics abdominal pain RR 4.04 (2.36-6.92) None

População: Adult IBS patients

Controlled Clinical Trial n=43 4 weeks
Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with …
Dose: 5 g/d vs: None Outcome: None Efeito: None None

População: IBS patients

Randomized Controlled Trial n=160 Double-blind
Food supplements and diet as treatment options in irritable bowel syndrome.
Dose: None vs: Placebo Outcome: None Efeito: None None

População: IBS patients

Meta-Analysis
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Dose: None vs: Placebo Outcome: efficacy of Western herbal medicines in the treatment … Efeito: None None

População: IBS patients

Key Statistics

3

Estudos

250

Participantes

Mixed

C

Nota

Referenced Papers

Neurogastroenterology and motility 2020 34 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule
ibssupport:
100 mL twice daily for 1-3 months
constipation:
100-300 mg aloe latex (short-term only, maximum 1-2 weeks)

Limite superior: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
None -- Mixed --
None -- Mixed --
None -- Positive --
5 g/d 4 weeks Positive 43
None -- Positive 160
None -- Positive --
500 mg 2.0 weeks Positive --
None -- Mixed --

Melhor horário: Before meals; aloe latex should only be used short-term for constipation

Safety & Side Effects

Efeitos Colaterais Relatados

  • Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products)
  • Electrolyte imbalance (hypokalemia) with chronic laxative use
  • Potential hepatotoxicity with long-term whole leaf consumption (rare)
  • Allergic skin reactions in sensitive individuals

Interações Conhecidas

  • Digoxin (hypokalemia from laxative use may increase digoxin toxicity)
  • Diuretics (additive potassium loss with aloe latex)
  • Diabetes medications (aloe may lower blood sugar; monitor glucose)
  • Stimulant laxatives (additive laxative effect; avoid combining)
  • Anticoagulants (theoretical interaction due to platelet effects)

Ingestão máxima tolerável: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Aloe Vera (Inner Leaf Gel) help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 250 participants, there is limited but promising evidence that Aloe Vera (Inner Leaf Gel) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Aloe Vera (Inner Leaf Gel) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Aloe Vera (Inner Leaf Gel)?
Reported side effects may include Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products), Electrolyte imbalance (hypokalemia) with chronic laxative use, Potential hepatotoxicity with long-term whole leaf consumption (rare), Allergic skin reactions in sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Aloe Vera (Inner Leaf Gel) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 250 total participants. The overall direction of effect is mixed.

Related Evidence

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.