What is the recommended dosage for Lactobacillus plantarum?

General: 10-20 billion CFU/day; Ibs Support: 10 billion CFU/day (299v strain) for 4 weeks minimum

What are the side effects of Lactobacillus plantarum?

Potential side effects include: Mild gas and bloating during initial use, Occasional loose stools, Histamine-related symptoms in sensitive individuals (histamine-producing species), Very rare: bacteremia in immunocompromised individuals.

What is Lactobacillus plantarum and how does it work for gut health?

Lactobacillus plantarum is a versatile probiotic found in fermented foods like sauerkraut, kimchi, and sourdough. It has a remarkable ability to survive stomach acid and bile, and produces antimicrobial substances that inhibit pathogens. Research suggests it may help reduce bloating, improve intestinal barrier function, and modulate immune responses, with particular evidence for IBS symptom relief.

What is the recommended dosage of Lactobacillus plantarum?

Studies have used dosages of 1 billion to 20 billion CFU per day. The strain L. plantarum 299v (LP299V) is the most clinically studied for IBS, typically at 10-20 billion CFU daily. It is available in both refrigerated and shelf-stable formulations, and can be taken with or without food.

Are there side effects or interactions with Lactobacillus plantarum?

L. plantarum is considered safe with a long history of use in traditional fermented foods. Side effects are rare and mild, typically limited to transient bloating. It has been well-tolerated in clinical trials even at high doses. No significant drug interactions have been reported, and it is one of the probiotic species with the broadest safety data.

Lactobacillus plantarum
Lactobacillus plantarum

probiotic_strain

다른 이름: L. plantarum, Lactiplantibacillus plantarum, 299v, WCFS1

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About

Lactobacillus plantarum is a versatile probiotic species with strong adhesion to the intestinal mucosa, allowing it to effectively compete with pathogens for binding sites. It produces plantaricin, a natural antimicrobial peptide, and may help modulate NF-kB inflammatory signaling in the gut. The 299v strain has been particularly well-studied for supporting digestive comfort in IBS.

How It Works

Adheres strongly to intestinal mucosa competing with pathogens for binding sites; produces plantaricin antimicrobial peptides with broad-spectrum activity; modulates NF-kB inflammatory signaling reducing pro-inflammatory cytokine production; enhances short-chain fatty acid production in the colon.

Evidence For Conditions

건강 상태	등급	연구	참여자
Irritable Bowel Syndrome (IBS)	B	5	800	보기 →

Side Effects

Mild gas and bloating during initial use
Occasional loose stools
Histamine-related symptoms in sensitive individuals (histamine-producing species)
Very rare: bacteremia in immunocompromised individuals

Drug & Supplement Interactions

Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
Immunosuppressants (theoretical risk in immunocompromised patients)
Histamine-intolerance medications (L. plantarum may produce biogenic amines)

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Related Ingredients

Lactobacillus gasseri Lactobacillus casei Lactobacillus rhamnosus GG Saccharomyces boulardii Bifidobacterium longum

핵심 정보

용량: General: 10-20 billion CFU/day; Ibs_Support: 10 billion CFU/day (299v strain) for 4 weeks minimum
제형: capsule powder sachet fermented foods
천연 원료: Sauerkraut, Kimchi, Pickled vegetables, Sourdough bread, Olives
상한 섭취량: Well-tolerated up to 20 billion CFU/day in clinical trials
권장 복용 시간: On an empty stomach or before meals

근거 요약

Irritable Bowel Syndrome (IBS) B

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.