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Aloe Vera (Inner Leaf Gel) के लिए Ulcerative Colitis (UC)

D

Single RCT showed aloe vera gel improved UC symptoms vs placebo. Very limited evidence; not replicated.

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D

निष्कर्ष

Single RCT showed aloe vera gel improved UC symptoms vs placebo. Very limited evidence; not replicated.

Key Study Findings

Review
Emerging Natural Therapies for the Treatment of Inflammatory Bowel Disease.
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: Review of natural therapies for IBD

In Vitro 1.0 weeks
Therapeutic Effects of Aloe saponaria against Ulcerative Colitis Induced by Dextran Sulfate Sodium.
Dose: 272 µg/ बनाम: vehicle Outcome: Ulcerative colitis severity प्रभाव: None None

जनसंख्या: Mice (DSS-induced colitis model)

Controlled Clinical Trial n=36 2 weeks
Aloe vera gel attenuates acetic acid-induced ulcerative colitis in adult male Wistar rats.
Dose: 20, 40, or 60 mg/kg b.wt. बनाम: Dexamethasone 1 mg/kg and normal saline Outcome: Clinical activity index, histological alterations, DNA, NO प्रभाव: None None

जनसंख्या: Adult male Wistar rats with acetic acid-induced UC

Review
Complementary medicines used in ulcerative colitis and unintended interactions with cytochrome P450-dependent drug-metabolizing enzymes.
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: Ulcerative colitis patients using CAM

Other
Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing …
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: None

Controlled Clinical Trial
Anti-Inflammatory, Antioxidant, and Healing-Promoting Effects of Aloe vera Extract in the Experimental Colitis in Rats.
Dose: None बनाम: Control without aloe vera Outcome: Anti-inflammatory, antioxidant, wound healing प्रभाव: None None

जनसंख्या: Animal/cell wound healing models

Key Statistics

1

अध्ययन

44

प्रतिभागी

Positive

D

ग्रेड

Referenced Papers

Current pharmaceutical biotechnology 2025 1 उद्धरण
Therapeutic advances in … 2020 21 उद्धरण
Annals of gastroenterology 2015 135 उद्धरण
World journal of … 2014 23 उद्धरण
Alimentary pharmacology & … 2013 128 उद्धरण
Saudi journal of … 2012 138 उद्धरण
Alimentary pharmacology & … 2006 181 उद्धरण
Health news (Waltham, … 2004 1 उद्धरण
The European journal … 1998 62 उद्धरण

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

general:
100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule
ibssupport:
100 mL twice daily for 1-3 months
constipation:
100-300 mg aloe latex (short-term only, maximum 1-2 weeks)

अधिकतम सीमा: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks

अनुसंधान में अध्ययन की गई खुराकें

खुराक अवधि प्रभाव N
None -- Mixed --
272 µg/ 1.0 weeks Positive --
20, 40, or 60 mg/kg b.wt. 2 weeks Positive 36
None -- Mixed --
None -- Mixed --
None -- Positive --
None -- Positive --
2 g 3 weeks Positive --

सेवन का सर्वोत्तम समय: Before meals; aloe latex should only be used short-term for constipation

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

  • Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products)
  • Electrolyte imbalance (hypokalemia) with chronic laxative use
  • Potential hepatotoxicity with long-term whole leaf consumption (rare)
  • Allergic skin reactions in sensitive individuals

ज्ञात अंतःक्रियाएँ

  • Digoxin (hypokalemia from laxative use may increase digoxin toxicity)
  • Diuretics (additive potassium loss with aloe latex)
  • Diabetes medications (aloe may lower blood sugar; monitor glucose)
  • Stimulant laxatives (additive laxative effect; avoid combining)
  • Anticoagulants (theoretical interaction due to platelet effects)

सहनीय अधिकतम सेवन: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Aloe Vera (Inner Leaf Gel) help with Ulcerative Colitis (UC)?
Based on 1 studies with 44 participants, there is preliminary evidence that needs more research that Aloe Vera (Inner Leaf Gel) may support Ulcerative Colitis (UC) management. Our evidence grade is D (Very Early Research).
How much Aloe Vera (Inner Leaf Gel) should I take for Ulcerative Colitis (UC)?
Studies have used various dosages. A commonly studied range is 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Aloe Vera (Inner Leaf Gel)?
Reported side effects may include Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products), Electrolyte imbalance (hypokalemia) with chronic laxative use, Potential hepatotoxicity with long-term whole leaf consumption (rare), Allergic skin reactions in sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Aloe Vera (Inner Leaf Gel) and Ulcerative Colitis (UC)?
We rate the evidence as Grade D (Very Early Research). This rating is based on 1 peer-reviewed studies with 44 total participants. The overall direction of effect is positive.

Related Evidence

इसके लिए अन्य सामग्री Ulcerative Colitis (UC)

Aloe Vera (Inner Leaf Gel) अन्य स्वास्थ्य स्थितियों के लिए

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।