Lactobacillus plantarum pour Irritable Bowel Syndrome (IBS)
BReduces abdominal pain and bloating in IBS. Multiple RCTs show significant improvement in global IBS symptom scores. Strain-specific evidence for 299v is relatively strong.
En conclusion
Reduces abdominal pain and bloating in IBS. Multiple RCTs show significant improvement in global IBS symptom scores. Strain-specific evidence for 299v is relatively strong.
Key Study Findings
Population: patients with irritable bowel syndrome
Population: patients with IBS from 32 RCTs evaluating 10 probiotic strains
Population: female rats with water avoidance stress-induced IBS-D model
Population: IBS patients from 52 Italian gastroenterologists
Population: C. rodentium + WAS IBS mouse model
Population: IBD patients with IBS symptoms in remission
Key Statistics
5
Études
800
Participants
Positive
Note
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Posologies couramment utilisées
- general:
- 10-20 billion CFU/day
- ibssupport:
- 10 billion CFU/day (299v strain) for 4 weeks minimum
Limite supérieure : Well-tolerated up to 20 billion CFU/day in clinical trials
Posologies étudiées dans la recherche
| Posologie | Durée | Effet | N |
|---|---|---|---|
| None | -- | Positive | 3154 |
| None | -- | Positive | -- |
| Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 | 4 weeks | Positive | 25 |
| None | 8 weeks | Positive | 1098 |
| 1e9 CFU/day + GOS 10 g/L | -- | Positive | -- |
| None | 12 weeks | Neutral | 61 |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Moment optimal de prise : On an empty stomach or before meals
Safety & Side Effects
Effets indésirables signalés
- ⚠ Mild gas and bloating during initial use
- ⚠ Occasional loose stools
- ⚠ Histamine-related symptoms in sensitive individuals (histamine-producing species)
- ⚠ Very rare: bacteremia in immunocompromised individuals
Interactions connues
- ● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
- ● Immunosuppressants (theoretical risk in immunocompromised patients)
- ● Histamine-intolerance medications (L. plantarum may produce biogenic amines)
Apport maximal tolérable : Well-tolerated up to 20 billion CFU/day in clinical trials
Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.
Frequently Asked Questions
Does Lactobacillus plantarum help with Irritable Bowel Syndrome (IBS)?
How much Lactobacillus plantarum should I take for Irritable Bowel Syndrome (IBS)?
Are there side effects of Lactobacillus plantarum?
How strong is the evidence for Lactobacillus plantarum and Irritable Bowel Syndrome (IBS)?
Related Evidence
Autres ingrédients pour Irritable Bowel Syndrome (IBS)
Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.