Vitamin D para Irritable Bowel Syndrome (IBS)
CLimited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
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C
Conclusión
Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
Key Study Findings
Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None
vs: None
Outcome: IBS symptom improvement with vitamin D supplementation
Efecto: None
None
Población: individuals with irritable bowel syndrome
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
vs: Various
Outcome: IBS symptom improvement
Efecto: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
Población: Adult IBS patients
Meta-Analysis
Double-blind
The effects of vitamin D intake and status on symptom severity and quality-of-life in adults …
Dose: 3,000 IU daily to 50,000 IU bi-weekly
vs: Placebo
Outcome: IBS symptom severity and quality of life
Efecto: MD 20.33 ng/mL [12.91, 27.74] for 25(OH)D; QoL 3.1
None
Población: Adults with IBS and deficient/insufficient vitamin D
Review
Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical review.
Dose: None
vs: None
Outcome: Risk of developing Parkinson's disease
Efecto: None
None
Población: General population (narrative review of PD risk factors)
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
Efecto: None
None
Población: Children with inflammatory bowel disease (review)
Review
Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
Dose: None
vs: None
Outcome: IBS symptom relief and pathophysiology modulation
Efecto: None
None
Población: Patients with irritable bowel syndrome (review)
Key Statistics
3
Estudios
400
Participantes
↑
Positive
C
Calificación
Referenced Papers
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None
4 citas
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
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2025
10 citas
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2025
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Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
Review
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4 citas
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2023
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Systematic Review
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3 citas
Irritable bowel syndrome and endometriosis: diagnosis, similarities, and nutritional management.
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2 citas
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Meta-Analysis
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Systematic Review
Journal of gastroenterology …
2022
29 citas
The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis.
Meta-Analysis
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2022
28 citas
The Effect of Vitamin D Supplementation on the Severity of Symptoms and the Quality of Life in Irritable Bowel Syndrome …
Meta-Analysis
Nutrients
2022
24 citas
PloS one
2022
10 citas
Nutricion hospitalaria
2022
9 citas
Association between Serum Vitamin D and Irritable Bowel Syndrome Symptoms in a Sample of Adults.
Other
Nutrients
2022
7 citas
Journal of gastroenterology …
2022
4 citas
Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.
Systematic Review
Nutrients
2021
16 citas
Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome.
Other
Journal of gastroenterology …
2021
10 citas
Zhongguo dang dai …
2021
The journal of …
2020
294 citas
The association between irritable bowel syndrome and osteoporosis: a systematic review and meta-analysis.
Meta-Analysis
Osteoporosis international : …
2020
14 citas
Cureus
2020
10 citas
Irritable bowel syndrome: a review of the general aspects and the potential role of vitamin D.
Review
Expert review of …
2019
33 citas
Medicine
2019
4 citas
Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what …
Systematic Review
European journal of …
2018
39 citas
Saudi journal of …
2018
38 citas
The Australian and …
2017
280 citas
Current gastroenterology reports
2017
157 citas
PloS one
2017
38 citas
PloS one
2017
5 citas
World journal of …
2016
238 citas
Nutrients
2016
55 citas
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Review
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2016
41 citas
Clinics in dermatology
2016
19 citas
World journal of …
2015
62 citas
Oman medical journal
2015
56 citas
Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.
Other
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2014
38 citas
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2012
225 citas
Inflammatory bowel diseases
2012
224 citas
Dietary supplements for established atopic eczema.
Meta-Analysis
The Cochrane database …
2012
130 citas
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2011
23 citas
Acta psychiatrica Scandinavica
1979
22 citas
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
Límite superior: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 3,000 IU daily to 50,000 IU bi-weekly | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 240 |
Mejor momento para tomar: With a meal containing fat for better absorption
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
Interacciones conocidas
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
Ingesta máxima tolerable: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Vitamin D help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 400 participants, there is limited but promising evidence that Vitamin D may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Vitamin D should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
Otros ingredientes para Irritable Bowel Syndrome (IBS)
Vitamin D para otras condiciones
Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.