Bacillus coagulans لـ Irritable Bowel Syndrome (IBS)

Q: Does Bacillus coagulans help with Irritable Bowel Syndrome (IBS)?

Based on 3 studies with 400 participants, there is moderate evidence from clinical studies that Bacillus coagulans may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).

Q: How much Bacillus coagulans should I take for Irritable Bowel Syndrome (IBS)?

Studies have used various dosages. A commonly studied range is 1-2 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Bacillus coagulans?

Reported side effects may include Mild gas during initial use (generally less than other probiotics due to spore form), Occasional bloating, Rare loose stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Bacillus coagulans and Irritable Bowel Syndrome (IBS)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Reduces abdominal pain, bloating, and diarrhea in IBS. Spore-forming nature provides excellent stability and gastric acid survival.

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'gutcited.com'; const params = 'ingredient\u003Dbacillus\u002Dcoagulans\u0026condition\u003Dibs'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

الخلاصة

Reduces abdominal pain, bloating, and diarrhea in IBS. Spore-forming nature provides excellent stability and gastric acid survival.

Key Study Findings

Meta-Analysis

Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome.

Dose: None مقابل: placebo Outcome: improvement in key IBS symptoms التأثير: None None

المجتمع المدروس: patients with IBS from 32 RCTs evaluating 10 probiotic strains

Randomized Controlled Trial n=61 4 weeks Double-blind

Effects of a Bacillus subtilis HU58 and Heyndrickxia faecalis SC208 spore-forming probiotic formula on gastrointestinal …

Dose: None مقابل: Placebo Outcome: Abdominal pain (NRS) and stool consistency (BSFS) التأثير: None P = 0.003 (pain); P = 0.035 (s

المجتمع المدروس: Adults with diarrhoea-predominant IBS (IBS-D)

Randomized Controlled Trial n=100 12 weeks

Role of Bacillus coagulans (Heyndrickxia coagulans)BCP92 in managing irritable bowel syndrome: A randomized, double-blind, multicenter, …

Dose: None مقابل: Control Outcome: Pain outcomes التأثير: None P < .001

المجتمع المدروس: IBS patients

Meta-Analysis

Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review …

Dose: Various probiotic strains/mixtures مقابل: Placebo Outcome: Outcome-specific efficacy ranking in IBS التأثير: None None

المجتمع المدروس: Adults with IBS (RCTs)

Randomized Controlled Trial 12 weeks Double-blind

The Efficacy and Safety of Single-Strain Probiotic Formulations Containing Bifidobacterium lactis or Bacillus coagulans in …

Dose: 20.5% مقابل: placebo Outcome: IBS symptom improvement التأثير: None p = 0.038

المجتمع المدروس: Adults with IBS

Review

Oral microbial shift induced by probiotic Bacillus coagualans along with its clinical perspectives.

Dose: None مقابل: None Outcome: colitis/IBD severity التأثير: None None

المجتمع المدروس: None

Key Statistics

الدراسات

400

المشاركون

↑

Positive

التقييم

Referenced Papers

Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome. Review

Journal of clinical … 2026

Effects of a Bacillus subtilis HU58 and Heyndrickxia faecalis SC208 spore-forming probiotic formula on gastrointestinal health: results of a randomised, … Other

Beneficial microbes 2026

Role of Bacillus coagulans (Heyndrickxia coagulans)BCP92 in managing irritable bowel syndrome: A randomized, double-blind, multicenter, placebo-controlled clinical trial. RCT

Medicine 2024 6 اقتباسات

Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Meta-Analysis

Nutrients 2023 33 اقتباسات

Oral microbial shift induced by probiotic Bacillus coagualans along with its clinical perspectives. Review

Journal of oral … 2023 12 اقتباسات

Effects of Glutamine, Curcumin and Fish Bioactive Peptides Alone or in Combination on Intestinal Permeability in a Chronic-Restraint Stress Model. Other

International journal of … 2023 9 اقتباسات

The Efficacy and Safety of Single-Strain Probiotic Formulations Containing Bifidobacterium lactis or Bacillus coagulans in Adult Patients with Irritable Bowel … Other

Journal of clinical … 2023 9 اقتباسات

Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study [CONSORT … RCT

Medicine 2021 45 اقتباسات

Impact of a Gastrointestinal Stable Probiotic Supplement Bacillus coagulans LBSC on Human Gut Microbiome Modulation. Other

Journal of dietary … 2021 33 اقتباسات

Is Bacillus coagulans supplementation plus low FODMAP diet superior to low FODMAP diet in irritable bowel syndrome management? RCT

European journal of … 2020 20 اقتباسات

Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management of irritable bowel … RCT

Scientific reports 2019 65 اقتباسات

Bacillus coagulans and its applications in medicine. Review

Beneficial microbes 2019 45 اقتباسات

Bacillus coagulans and its applications in medicine. Other

Beneficial microbes 2019 29 اقتباسات

Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, … Other

Food & nutrition … 2018 162 اقتباسات

Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double blind, randomised placebo controlled … RCT

Beneficial microbes 2018 59 اقتباسات

Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled … RCT

Nutrition journal 2016 102 اقتباسات

A randomized double-blind placebo-controlled clinical trial on efficacy and safety of association of simethicone and Bacillus coagulans (Colinox®) in patients … RCT

European review for … 2014 33 اقتباسات

The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial. Other

Gastroenterology and hepatology … 2014

Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS. RCT

Postgraduate medicine 2009 144 اقتباسات

Effects of a proprietary Bacillus coagulans preparation on symptoms of diarrhea-predominant irritable bowel syndrome. RCT

Methods and findings … 2009 104 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:: 1-2 billion CFU/day
ibssupport:: 2 billion CFU/day (GBI-30 6086 strain)

الحد الأعلى: Well-tolerated up to 6 billion CFU/day in clinical trials

الجرعات المدروسة في الأبحاث

الجرعة	المدة	التأثير	ن
None	--	Positive	--
None	4 weeks	Positive	61
None	12 weeks	Positive	100
Various probiotic strains/mixtures	--	Positive	--
20.5%	12 weeks	Positive	--
None	--	Positive	--
None	--	Mixed	--
None	--	Mixed	--

أفضل وقت للتناول: With meals for optimal spore germination and colonization

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

⚠ Mild gas during initial use (generally less than other probiotics due to spore form)
⚠ Occasional bloating
⚠ Rare loose stools

التفاعلات المعروفة

● Antibiotics (spore form is more resistant than vegetative probiotics, but spacing still recommended)
● Immunosuppressants (theoretical risk in immunocompromised patients)

الحد الأقصى المسموح به: Well-tolerated up to 6 billion CFU/day in clinical trials

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Bacillus coagulans help with Irritable Bowel Syndrome (IBS)?

Based on 3 studies with 400 participants, there is moderate evidence from clinical studies that Bacillus coagulans may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).

How much Bacillus coagulans should I take for Irritable Bowel Syndrome (IBS)?

Studies have used various dosages. A commonly studied range is 1-2 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Bacillus coagulans?

Reported side effects may include Mild gas during initial use (generally less than other probiotics due to spore form), Occasional bloating, Rare loose stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Bacillus coagulans and Irritable Bowel Syndrome (IBS)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

مكونات أخرى لـ Irritable Bowel Syndrome (IBS)

Peppermint Oil A Psyllium Husk B Lactobacillus rhamnosus GG B Partially Hydrolyzed Guar Gum (PHGG) B Lactobacillus plantarum B Bifidobacterium longum B

الخلاصة السريعة

Reduces abdominal pain, bloating, and diarrhea in IBS. Spore-forming nature provides excellent stability and gastric acid survival.

Evidence Strength72%

High confidence

تفصيل الدراسات

RCT (9)Meta (1)Other (0)

قارن البدائل

اعرف كيف تقارن المكونات الأخرى لهذه الحالة.

عرض جميع المكونات لـ Irritable Bowel Syndrome (IBS)

اعرف المزيد

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.