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Time-course analysis of IBS symptom improvement shows progressive benefit beginning at week 2 of probiotic treatment. Maximum improvement is typically achieved by week 6 to 8.

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![Figure 18: Time-course analysis of IBS symptom improvement shows progressive benefit beginning at week 2 of probiotic treatment. Maximum improvement is typically achieved by week 6 to 8.]()

> Source: Konstantinos Leventogiannis et al. "Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritabl." *Probiotics and antimicrobial proteins*, 2019. PMID: [29508268](https://pubmed.ncbi.nlm.nih.gov/29508268/)
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  <img src="" alt="Time-course analysis of IBS symptom improvement shows progressive benefit beginning at week 2 of probiotic treatment. Maximum improvement is typically achieved by week 6 to 8." />
  <figcaption>Figure 18. Time-course analysis of IBS symptom improvement shows progressive benefit beginning at week 2 of probiotic treatment. Maximum improvement is typically achieved by week 6 to 8.<br>  Source: Konstantinos Leventogiannis et al. "Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritabl." <em>Probiotics and antimicrobial proteins</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29508268/">29508268</a></figcaption>
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