Lactobacillus reuteri untuk Bloating and Intestinal Gas

Q: Does Lactobacillus reuteri help with Bloating and Intestinal Gas?

Based on 7 studies with 500 participants, there is moderate evidence from clinical studies that Lactobacillus reuteri may support Bloating and Intestinal Gas management. Our evidence grade is B (Good Evidence).

Q: How much Lactobacillus reuteri should I take for Bloating and Intestinal Gas?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Lactobacillus reuteri and Bloating and Intestinal Gas?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

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Kesimpulan

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

Key Study Findings

basic science

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.

Dose: Lactobacillus reuteri E9 (dose not specified) vs: Placebo Efek: None < 0.05

Observational Study n=65 Open-label

Incidence and Characterization of SIBO in NAFLD Patients.

Dose: None vs: None Outcome: SIBO prevalence in NAFLD patients Efek: SIBO in 37%; post-treatment 4% remained+ None

Populasi: Adults with NAFLD diagnosed via FibroScan

Randomized Controlled Trial n=56 15 weeks Double-blind

Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and …

Dose: 4x10^8 CFU (induction), 2x10^8 CFU (standard) vs: Placebo Outcome: Constipation symptoms and QoL (Constipaq/CSS) Efek: None pP0.05

Populasi: Adults with functional constipation

Other n=54 Double-blind

Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, …

Dose: None vs: Simethicone Outcome: Safety and efficacy for functional bloating Efek: None pP0.008

Populasi: Adults with functional bloating

Meta-Analysis n=3122

Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a …

Dose: None vs: Triple therapy alone/placebo Outcome: H. pylori eradication rate and side effects Efek: None None

Populasi: Children with H. pylori infection

Randomized Controlled Trial n=101 16 weeks Double-blind

Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, …

Dose: L. reuteri DSM 17938 (1e8 CFU twice daily) vs: placebo Outcome: abdominal pain severity (Wong-Baker FACES) Efek: None None

Populasi: Children aged 6-15 with functional abdominal pain

Key Statistics

Studi

500

Peserta

↑

Positive

Peringkat

Referenced Papers

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA. Other

Frontiers in bioscience … 2025

Incidence and Characterization of SIBO in NAFLD Patients. Other

Euroasian journal of … 2025

Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and bowel habit in functional constipation. RCT

Beneficial microbes 2018 35 sitasi

Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, randomised, double-blind, parallel group, clinical … Other

Translational gastroenterology and … 2018 24 sitasi

Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Meta-Analysis

European journal of … 2017 93 sitasi

Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, Double-Blind, Placebo-Controlled Trial. RCT

The Journal of … 2016 84 sitasi

Probiotic vs. Placebo in Irritable Bowel Syndrome:A Randomized Controlled Trial. Other

Middle East journal … 2013 13 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 100 million - 5 billion CFU/day
infantilecolic:: 100 million CFU/day (DSM 17938 strain, 5 drops)
adultgisupport:: 1-5 billion CFU/day

Batas atas: Well-tolerated up to 10 billion CFU/day in clinical trials

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
Lactobacillus reuteri E9 (dose not specified)	--	Positive	--
None	--	Positive	65
4x10^8 CFU (induction), 2x10^8 CFU (standard)	15 weeks	Positive	56
None	--	Positive	54
None	--	Positive	3122
L. reuteri DSM 17938 (1e8 CFU twice daily)	16 weeks	Positive	101
None	4 weeks	Positive	--

Waktu terbaik diminum: Before meals or on empty stomach; for infants, add drops to breast milk or formula

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Mild gas in initial days of use
⚠ Occasional increased fussiness in infants during adjustment (transient)
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

Interaksi yang Diketahui

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (theoretical risk in immunocompromised patients)
● Proton pump inhibitors (altered gastric pH may affect colonization)

Asupan atas yang dapat ditoleransi: Well-tolerated up to 10 billion CFU/day in clinical trials

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Lactobacillus reuteri help with Bloating and Intestinal Gas?

Based on 7 studies with 500 participants, there is moderate evidence from clinical studies that Lactobacillus reuteri may support Bloating and Intestinal Gas management. Our evidence grade is B (Good Evidence).

How much Lactobacillus reuteri should I take for Bloating and Intestinal Gas?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lactobacillus reuteri and Bloating and Intestinal Gas?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Bloating and Intestinal Gas

Pancreatic Enzymes (Pancrelipase) A Ginger B Alpha-Galactosidase B Medium-Chain Triglycerides (MCT Oil) C

Lactobacillus reuteri untuk kondisi lain

Gastroesophageal Reflux Disease (GERD) C

Kesimpulan Singkat

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

Evidence Strength72%

High confidence

Rincian Studi

RCT (2)Meta (1)Other (4)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Bloating and Intestinal Gas

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.