Vitamin D चित्र
5 सहकर्मी-समीक्षित शोध से आंकड़े
Vitamin D receptor expression and vitamin D-activating enzyme CYP27B1 are present in human colonic epithelial cells, enabling local production of active calcitriol. This paracrine signaling enhances tight junction integrity and antimicrobial defense at the mucosal surface.
The Role of Vitamin D in Inflammatory Bowel Disease: Mechanism to Management.
Epithelial mechanisms of vitamin D in IBD, illustrating VDR-mediated NF-kB suppression, claudin-2 regulation at the paracellular barrier, and other pathways through which vitamin D influences intestinal inflammation.
Managing vitamin D deficiency in inflammatory bowel disease.
Vitamin D's multifaceted role as an immune modulator is discussed, noting that nearly all immune cells express the vitamin D receptor and that deficiency is closely correlated with increased susceptibility to immune-mediated diseases.
The Role of Vitamin D in Immune System and Inflammatory Bowel Disease.
Vitamin D impacts on innate and adaptive immunity are illustrated, showing inhibition of LPS-induced p38 activation, suppression of IL-6 and TNF-alpha by monocytes, and downregulation of TLR-9 expression in immune cells.
The Role of Vitamin D in Immune System and Inflammatory Bowel Disease.