Galactooligosaccharides (GOS) para Irritable Bowel Syndrome (IBS)
BReduces IBS symptoms (pain, bloating, flatulence) in dose-dependent manner. 3.5 g/day showed better results than 7 g/day (excess fermentation at higher dose).
Conclusión
Reduces IBS symptoms (pain, bloating, flatulence) in dose-dependent manner. 3.5 g/day showed better results than 7 g/day (excess fermentation at higher dose).
Key Study Findings
Población: review of prebiotics, probiotics, synbiotics, postbiotics for gastrointestinal inflammation
Población: IBS patients (Rome IV) who improved on FODMAP diet
Población: IBS-D patients (Rome IV)
Población: Adult IBS patients
Población: Adults with constipation-predominant IBS
Población: Laboratory food science study (no human subjects)
Key Statistics
3
Estudios
400
Participantes
Positive
Calificación
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosificaciones de uso común
- general:
- 2.5-5 g/day
- ibssupport:
- 3.5 g/day (optimal dose; higher doses may increase symptoms)
- infantgutsupport:
- 0.24-0.48 g/100 mL formula (added to infant formula)
Límite superior: Well-tolerated up to 15 g/day; optimal dose appears to be 3.5-5 g/day
Dosificaciones estudiadas en la investigación
| Dosificación | Duración | Efecto | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | 12 weeks | Negative | 45 |
| None | 4 weeks | Mixed | -- |
| None | -- | Positive | -- |
| 9.2 g/day total (4.6 g twice daily) | 8 weeks | Positive | 34 |
| None | -- | Positive | -- |
| 1e9 CFU/day + GOS 10 g/L | -- | Positive | -- |
| None | -- | Neutral | -- |
Mejor momento para tomar: With meals; start with lower dose and increase gradually
Safety & Side Effects
Efectos secundarios reportados
- ⚠ Gas and bloating (especially above 5 g/day; dose-response is U-shaped)
- ⚠ Flatulence at higher doses
- ⚠ Abdominal cramping if dose increased too quickly
- ⚠ May worsen symptoms in FODMAP-sensitive individuals
Interacciones conocidas
- ● Other FODMAPs (cumulative fermentation in sensitive individuals)
- ● Lactose-containing products (GOS is derived from lactose; generally safe for lactose-intolerant individuals as GOS itself is lactose-free)
Ingesta máxima tolerable: Well-tolerated up to 15 g/day; optimal dose appears to be 3.5-5 g/day
Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.
Frequently Asked Questions
Does Galactooligosaccharides (GOS) help with Irritable Bowel Syndrome (IBS)?
How much Galactooligosaccharides (GOS) should I take for Irritable Bowel Syndrome (IBS)?
Are there side effects of Galactooligosaccharides (GOS)?
How strong is the evidence for Galactooligosaccharides (GOS) and Irritable Bowel Syndrome (IBS)?
Related Evidence
Otros ingredientes para Irritable Bowel Syndrome (IBS)
Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.