N-Acetyl Cysteine (NAC)N-Acetyl Cysteine (NAC)
amino_acid
别名: NAC, N-Acetylcysteine, Acetylcysteine
About
N-acetyl cysteine (NAC) is a precursor to glutathione, the body's master antioxidant, and may help restore mucosal antioxidant defenses in the GI tract. It also acts as a mucolytic agent, breaking disulfide bonds in mucus to reduce viscosity. Research suggests NAC may help modulate NF-kB signaling to support a healthy intestinal inflammatory response and may play a role in supporting H. pylori eradication by disrupting bacterial biofilm.
How It Works
Precursor to glutathione restoring mucosal antioxidant defenses; breaks disulfide bonds in mucus reducing viscosity (mucolytic action); modulates NF-kB signaling reducing intestinal inflammation; disrupts bacterial biofilm (relevant to H. pylori eradication); protects against NSAID-induced gastropathy.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| Helicobacter pylori Infection | C | 3 | 250 | 查看 → |
| Inflammatory Bowel Disease (IBD) — General | D | 1 | 30 | 查看 → |
Side Effects
- Nausea and vomiting (most common, especially at higher doses)
- Diarrhea
- Unpleasant sulfur taste/odor
- Headache
Drug & Supplement Interactions
- Nitroglycerin (NAC may enhance vasodilatory effects; risk of hypotension)
- Activated charcoal (may reduce NAC absorption)
- Anticoagulants (NAC may have mild antiplatelet effects)
- ACE inhibitors (additive hypotensive effect with nitroglycerin combination)
请务必告知您的医疗保健提供者您正在服用的所有补充剂。
Related Ingredients
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