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Lactobacillus reuteri 관련 Gastroesophageal Reflux Disease (GERD)

C

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

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            C

        

        

            
결론

            
            
Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    basic science
                
                
                
                
            

            
                Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.
            
            

                
                Dose: Lactobacillus reuteri E9 (dose not specified)
                
                
                vs: Placebo
                
                
                
                효과: None
                
                
                < 0.05
                
            

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                The evidence for probiotics in the treatment of digestive disorders in the pediatric population.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                효과: None
                
                
                None
                
            

            
            
대상 집단: Pediatric population

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
연구

    

    

        
250

        
참여자

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
등급

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            The evidence for probiotics in the treatment of digestive disorders in the pediatric population.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Journal of gastroenterology …
                        2025
                        
                        10 인용
                        
                    

                

                
                

                    

                        
                            Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Frontiers in bioscience …
                        2025
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
일반적으로 사용되는 용량

                

                    
                    

                        
general:

                        
100 million - 5 billion CFU/day

                    

                    
                    

                        
infantilecolic:

                        
100 million CFU/day (DSM 17938 strain, 5 drops)

                    

                    
                    

                        
adultgisupport:

                        
1-5 billion CFU/day

                    

                    
                

                
                

                    상한량: Well-tolerated up to 10 billion CFU/day in clinical trials
                

                
            

            

            
            

                
연구에서 사용된 용량

                

                    

                        
                            

                                용량
                                기간
                                효과
                                N
                            

                        
                        
                            
                            

                                Lactobacillus reuteri E9 (dose not specified)
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                권장 복용 시간: Before meals or on empty stomach; for infants, add drops to breast milk or formula
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
보고된 부작용

                    
    
                        
                        
  • 
                            ⚠
                            Mild gas in initial days of use
                        
    • 
                        
                        
  • 
                            ⚠
                            Occasional increased fussiness in infants during adjustment (transient)
                        
    • 
                        
                        
  • 
                            ⚠
                            Rare loose stools
                        
    • 
                        
                        
  • 
                            ⚠
                            Very rare: bacteremia in immunocompromised individuals
                        
    • 
                        
                    

                

                

                
                

                    
알려진 상호작용

                    
    
                        
                        
  • 
                            ●
                            Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
                        
    • 
                        
                        
  • 
                            ●
                            Immunosuppressants (theoretical risk in immunocompromised patients)
                        
    • 
                        
                        
  • 
                            ●
                            Proton pump inhibitors (altered gastric pH may affect colonization)
                        
    • 
                        
                    

                

                

                
                

                    

                        일일 최대 섭취 허용량: Well-tolerated up to 10 billion CFU/day in clinical trials
                    

                

                
            

            

                건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Lactobacillus reuteri help with Gastroesophageal Reflux Disease (GERD)?
            
        
        

            Based on 2 studies with 250 participants, there is limited but promising evidence that Lactobacillus reuteri may support Gastroesophageal Reflux Disease (GERD) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Lactobacillus reuteri should I take for Gastroesophageal Reflux Disease (GERD)?
            
        
        

            Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Lactobacillus reuteri?
            
        
        

            Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Lactobacillus reuteri and Gastroesophageal Reflux Disease (GERD)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
관련 다른 성분: Gastroesophageal Reflux Disease (GERD)

                    

                        
                        
                            Lactobacillus gasseri
                            D

                        
                        
                        
                            Ginger
                            D

                        
                        
                        
                            Slippery Elm
                            D

                        
                        
                    

                

                

                
                

                    
Lactobacillus reuteri 다른 건강 상태에 대한 근거

                    

                        
                        
                            Bloating and Intestinal Gas
                            B

                        
                        
                    

                

                
            

        

        

    


    
    












    

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        이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.