What is the recommended dosage for Bifidobacterium bifidum?

General: 1-10 billion CFU/day; Dyspepsia Support: 1 billion CFU/day (YIT 10347 strain)

What are the side effects of Bifidobacterium bifidum?

Potential side effects include: Mild gas and bloating during initial use, Occasional abdominal discomfort, Rare loose stools, Very rare: bacteremia in immunocompromised individuals.

What is Bifidobacterium bifidum and how does it work for gut health?

Bifidobacterium bifidum is a probiotic bacterium naturally found in the human gut, particularly abundant in infants. It helps break down dietary fiber, produces short-chain fatty acids that nourish intestinal cells, and competes with harmful bacteria for resources and attachment sites. Research suggests it may support immune function and help maintain the integrity of the intestinal barrier.

What is the recommended dosage of Bifidobacterium bifidum?

Clinical studies have used dosages ranging from 1 billion to 10 billion CFU per day, with most trials using 5-10 billion CFU. It is often included in multi-strain probiotic formulations. Refrigerated products typically maintain better viability, though some shelf-stable formulations are also available.

Are there side effects or interactions with Bifidobacterium bifidum?

Bifidobacterium bifidum has an excellent safety profile and is generally well-tolerated. Some individuals may experience mild bloating or gas during the initial days of supplementation as the gut microbiome adjusts. Immunocompromised individuals should consult their healthcare provider before starting any probiotic supplement.

Bifidobacterium bifidum

probiotic_strain

Also known as: B. bifidum, YIT 10347, Bb-06

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About

Bifidobacterium bifidum is a probiotic species that adheres to gastric epithelial cells and may support mucin secretion in the stomach. Research suggests it may help modulate NF-kB signaling to support a healthy gastric inflammatory response and promote microbial diversity. The YIT 10347 strain has been studied for its role in supporting digestive comfort in functional dyspepsia.

How It Works

Adheres to gastric epithelial cells promoting protective mucin secretion; regulates NF-kB signaling to reduce gastric inflammation and oxidative stress; restores microbial diversity in the upper and lower GI tract; produces exopolysaccharides with immunomodulatory properties.

Evidence For Conditions

Condition	Grade	Studies	Participants
Functional Dyspepsia	C	4	500	View →

Side Effects

Mild gas and bloating during initial use
Occasional abdominal discomfort
Rare loose stools
Very rare: bacteremia in immunocompromised individuals

Drug & Supplement Interactions

Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
Immunosuppressants (use with caution in immunocompromised patients)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Bacillus coagulans Bifidobacterium breve Bifidobacterium lactis Bifidobacterium longum Lactobacillus acidophilus

Quick Facts

Dosage: General: 1-10 billion CFU/day; Dyspepsia_Support: 1 billion CFU/day (YIT 10347 strain)
Forms: capsule powder sachet
Natural Sources: Breast milk, Human GI tract (commensal from birth), Fermented dairy products
Upper Limit: Well-tolerated up to 10 billion CFU/day in clinical trials
Best Time: On an empty stomach or before meals

Evidence Summary

Functional Dyspepsia C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.