Zinc Carnosine untuk Peptic Ulcer Disease

Reduces NSAID-induced small bowel injury by 70% (measured by calprotectin). Promotes gastric mucosal healing. 75-150 mg/day as zinc carnosine complex.

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Kesimpulan

Reduces NSAID-induced small bowel injury by 70% (measured by calprotectin). Promotes gastric mucosal healing. 75-150 mg/day as zinc carnosine complex.

Key Study Findings

Randomized Controlled Trial n=92

Zinc carnosine-based modified bismuth quadruple therapy vs standard triple therapy for Helicobacter pylori eradication: A …

Dose: Zinc carnosine 75 mg twice daily for 10 days vs: Standard triple therapy for 14 days Outcome: H. pylori eradication rate Efek: 93.5% vs 69.6% P=0.003

Populasi: Dyspepsia patients with H. pylori infection

In Vitro

The membrane-stabilizing action of zinc carnosine (Z-103) in stress-induced gastric ulceration in rats.

Dose: 30 mg/kg vs: None Outcome: mineral status Efek: or 2 None

Populasi: animal model

Key Statistics

Studi

500

Peserta

↑

Positive

Peringkat

Referenced Papers

Zinc carnosine-based modified bismuth quadruple therapy vs standard triple therapy for Helicobacter pylori eradication: A randomized controlled study. Other

World journal of … 2022 8 sitasi

The membrane-stabilizing action of zinc carnosine (Z-103) in stress-induced gastric ulceration in rats. Other

Life sciences 1991 52 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 75 mg twice daily (as zinc carnosine complex)
nsaidprotection:: 37.5-75 mg twice daily alongside NSAID therapy
gastricprotection:: 75 mg twice daily for 8 weeks

Batas atas: 40 mg/day elemental zinc (equivalent to ~340 mg zinc carnosine); risk of copper depletion above this

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
Zinc carnosine 75 mg twice daily for 10 days	--	Positive	92
30 mg/kg	--	Positive	--

Waktu terbaik diminum: On an empty stomach or between meals for gastric mucosal contact; twice daily

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Nausea (most common, usually transient)
⚠ Metallic taste
⚠ Copper depletion with long-term high-dose use (>40 mg elemental zinc/day)
⚠ Headache

Interaksi yang Diketahui

● Tetracycline and quinolone antibiotics (zinc reduces absorption; space 2 hours)
● Penicillamine (zinc reduces absorption)
● Copper supplements (zinc competes with copper for absorption)
● Bisphosphonates (zinc may reduce absorption; space 2 hours)

Asupan atas yang dapat ditoleransi: 40 mg/day elemental zinc (equivalent to ~340 mg zinc carnosine); risk of copper depletion above this

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Zinc Carnosine help with Peptic Ulcer Disease?

Based on 6 studies with 500 participants, there is moderate evidence from clinical studies that Zinc Carnosine may support Peptic Ulcer Disease management. Our evidence grade is B (Good Evidence).

How much Zinc Carnosine should I take for Peptic Ulcer Disease?

Studies have used various dosages. A commonly studied range is 75 mg twice daily (as zinc carnosine complex). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Zinc Carnosine?

Reported side effects may include Nausea (most common, usually transient), Metallic taste, Copper depletion with long-term high-dose use (>40 mg elemental zinc/day), Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Zinc Carnosine and Peptic Ulcer Disease?

We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Related Evidence

Bahan lain untuk Peptic Ulcer Disease

Deglycyrrhizinated Licorice (DGL) C

Zinc Carnosine untuk kondisi lain

Increased Intestinal Permeability (Leaky Gut) C

Kesimpulan Singkat

Reduces NSAID-induced small bowel injury by 70% (measured by calprotectin). Promotes gastric mucosal healing. 75-150 mg/day as zinc carnosine complex.

Evidence Strength72%

High confidence

Rincian Studi

RCT (0)Meta (0)Other (6)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Peptic Ulcer Disease

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.