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Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial.

K H Pitkala, T E Strandberg, U H Finne Soveri, A C Ouwehand, T Poussa et al.
RCT The journal of nutrition, health & aging 2007
PubMed
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Study Design

研究类型
Randomized Controlled Trial
研究人群
12 wards in two nursing homes in Finland
持续时间
30.099999999999998 weeks
干预措施
Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial. None
对照组
None
主要结局
Fermented cereal with specific bifidobacteria normalizes bowel movements in elde
效应方向
Mixed
偏倚风险
Low

Abstract

OBJECTIVE: To assess how fermented oat drink with two selected Bifidobacterium longum strains influences bowel movements among elderly nursing home residents. DESIGN: A randomized, double-blind, placebo-controlled trial. SETTING: 12 wards in two nursing homes in Finland. PARTICIPANTS: 209 residents. INTERVENTION: Wards were randomized to receive daily a fermented oat drink with 1) 109 CFU/day Bifidobacterium longum strains or 2) 109 CFU/day Bifidobacterium lactis Bb12 or 3) without viable bacteria (placebo) for 7 months. MEASUREMENTS: Regularity of bowel movements (no movements or functioning) and consistency of stools (normal, soft or diarrhoea) were recorded for each resident on a daily basis. RESULTS: The fermented oat drinks were well taken by the subjects, compliance being 85%. The groups receiving active products had more frequent bowel movements than did the placebo group (B. longum group normal functioning 28.5% of follow-up days, B.lactis group 26.9%, and placebo group 20.0%, respectively). The differences between the B. longum and the placebo group (mean 7.1, 95% CI 2.3 - 11.9, p=0.004) and between the B.lactis group and the placebo (mean 6.7, 95% CI 2.5 - 10.9, p = 0.002) were significant even when diarrhoea and constipation in the 3 months prior to the study were used as covariates. CONCLUSIONS: It is possible to normalize bowel movements in frail nursing home.

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