Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial.
Study Design
- 研究类型
- Randomized Controlled Trial
- 研究人群
- 12 wards in two nursing homes in Finland
- 持续时间
- 30.099999999999998 weeks
- 干预措施
- Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial. None
- 对照组
- None
- 主要结局
- Fermented cereal with specific bifidobacteria normalizes bowel movements in elde
- 效应方向
- Mixed
- 偏倚风险
- Low
Abstract
OBJECTIVE: To assess how fermented oat drink with two selected Bifidobacterium longum strains influences bowel movements among elderly nursing home residents. DESIGN: A randomized, double-blind, placebo-controlled trial. SETTING: 12 wards in two nursing homes in Finland. PARTICIPANTS: 209 residents. INTERVENTION: Wards were randomized to receive daily a fermented oat drink with 1) 109 CFU/day Bifidobacterium longum strains or 2) 109 CFU/day Bifidobacterium lactis Bb12 or 3) without viable bacteria (placebo) for 7 months. MEASUREMENTS: Regularity of bowel movements (no movements or functioning) and consistency of stools (normal, soft or diarrhoea) were recorded for each resident on a daily basis. RESULTS: The fermented oat drinks were well taken by the subjects, compliance being 85%. The groups receiving active products had more frequent bowel movements than did the placebo group (B. longum group normal functioning 28.5% of follow-up days, B.lactis group 26.9%, and placebo group 20.0%, respectively). The differences between the B. longum and the placebo group (mean 7.1, 95% CI 2.3 - 11.9, p=0.004) and between the B.lactis group and the placebo (mean 6.7, 95% CI 2.5 - 10.9, p = 0.002) were significant even when diarrhoea and constipation in the 3 months prior to the study were used as covariates. CONCLUSIONS: It is possible to normalize bowel movements in frail nursing home.
Used In Evidence Reviews
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