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Neuroinflammatory marker expression in brain tissue of APOE4 mice demonstrates that inulin supplementation is associated with reduced glial activation and lower pro-inflammatory cytokine levels, with notable sex-dependent variation.

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Source Paper

Prebiotic inulin enhances gut microbial metabolism and anti-inflammation in apolipoprotein E4 mice with sex-specific implications.

Scientific reports (2023)

PMID: 37704738

DOI: 10.1038/s41598-023-42381-x

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![Figure 4: Neuroinflammatory marker expression in brain tissue of APOE4 mice demonstrates that inulin supplementation is associated with reduced glial activation and lower pro-inflammatory cytokine levels, with notable sex-dependent variation.]()

> Source: Ya-Hsuan Chang et al. "Prebiotic inulin enhances gut microbial metabolism and anti-inflammation in apol." *Scientific reports*, 2023. PMID: [37704738](https://pubmed.ncbi.nlm.nih.gov/37704738/)

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  <img src="" alt="Neuroinflammatory marker expression in brain tissue of APOE4 mice demonstrates that inulin supplementation is associated with reduced glial activation and lower pro-inflammatory cytokine levels, with notable sex-dependent variation." />
  <figcaption>Figure 4. Neuroinflammatory marker expression in brain tissue of APOE4 mice demonstrates that inulin supplementation is associated with reduced glial activation and lower pro-inflammatory cytokine levels, with notable sex-dependent variation.<br>  Source: Ya-Hsuan Chang et al. "Prebiotic inulin enhances gut microbial metabolism and anti-inflammation in apol." <em>Scientific reports</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/37704738/">37704738</a></figcaption>
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