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GutCited

Slippery Elm

herb

Also known as: Ulmus rubra, Ulmus fulva, Red Elm, Indian Elm, Moose Elm

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About

Slippery elm (Ulmus rubra) inner bark contains mucilage polysaccharides that form a soothing protective gel when mixed with water. This gel may coat and protect the esophageal and gastric mucosa, providing temporary relief from irritation. It may also help stimulate mucus secretion from goblet cells and contains antioxidant tannins. While traditionally used for centuries, clinical trial data remains very limited.

How It Works

Mucilage polysaccharides form a protective gel coating the esophageal and gastric mucosa on contact; stimulates mucus secretion from goblet cells via mechanoreceptor activation; antioxidant tannins reduce mucosal oxidative stress; demulcent action provides physical barrier against acid irritation.

Evidence For Conditions

Side Effects

  • May slow absorption of oral medications due to mucilage coating (space 1-2 hours)
  • Rare allergic reactions (contact dermatitis reported)
  • Mild nausea in some individuals
  • Potential for contaminants in unregulated products

Drug & Supplement Interactions

  • May reduce absorption of oral medications by coating the GI tract (space 1-2 hours from all oral meds)
  • No significant pharmacological interactions known

Always inform your healthcare provider about all supplements you take.

Related Ingredients

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.