Resistant Starch
prebioticAlso known as: RS, RS2 (raw potato starch), RS3 (retrograded starch), Hi-Maize, Green banana starch
About
Resistant starch is a type of starch that escapes digestion in the small intestine and is fermented by colonic bacteria, making it the most potent natural butyrate producer among prebiotics. Research suggests it may help increase fecal butyrate concentration by 30-40%, supporting colonic cell health and gut barrier function. It feeds key butyrate-producing species including Ruminococcus bromii and Eubacterium rectale.
How It Works
Escapes small intestine digestion reaching the colon intact; fermented primarily to butyrate (highest butyrate-producing prebiotic) by Ruminococcus bromii and Eubacterium rectale; increases fecal butyrate concentration by 30-40%; supports colonocyte energy metabolism and tight junction integrity.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Increased Intestinal Permeability (Leaky Gut) | C | 4 | 300 | View → |
| Ulcerative Colitis (UC) | D | 1 | 40 | View → |
Side Effects
- Gas and bloating (common initially; typically resolves in 2-4 weeks)
- Flatulence (more pronounced than other prebiotics)
- Abdominal discomfort during adaptation period
- Loose stools if introduced too quickly
Drug & Supplement Interactions
- Blood sugar-lowering medications (resistant starch may improve insulin sensitivity)
- Other high-fiber foods (cumulative fermentation effect)
Always inform your healthcare provider about all supplements you take.
Related Ingredients
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