What is the recommended dosage for Lactobacillus reuteri?

General: 100 million - 5 billion CFU/day; Infantile Colic: 100 million CFU/day (DSM 17938 strain, 5 drops); Adult Gi Support: 1-5 billion CFU/day

What are the side effects of Lactobacillus reuteri?

Potential side effects include: Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals.

What is Lactobacillus reuteri and how does it work for gut health?

Lactobacillus reuteri is a probiotic species that naturally colonizes the human gut and produces reuterin, a broad-spectrum antimicrobial compound. It has been studied for its ability to reduce H. pylori infection, improve gut motility, and reduce infantile colic. L. reuteri is unique among probiotics in its documented ability to produce a compound that directly inhibits a wide range of pathogenic microorganisms.

What is the recommended dosage of Lactobacillus reuteri?

The most studied strains are L. reuteri DSM 17938 and ATCC PTA 6475, typically dosed at 100 million to 10 billion CFU per day. For infantile colic, 100 million CFU daily has shown efficacy. For adult digestive health, 1-10 billion CFU per day is commonly used. The probiotic is often taken as drops, chewable tablets, or capsules.

Are there side effects or interactions with Lactobacillus reuteri?

L. reuteri has an excellent safety profile in both infants and adults across numerous clinical trials. Side effects are uncommon and typically mild. When used as an adjunct to H. pylori eradication therapy, it may help reduce antibiotic-related side effects. Standard precautions for probiotics apply to immunocompromised individuals.

Lactobacillus reuteri

probiotic_strain

Also known as: L. reuteri, Limosilactobacillus reuteri, DSM 17938, ATCC 55730, BioGaia

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About

Lactobacillus reuteri is one of the few probiotic species that naturally colonizes the human GI tract from infancy. It produces reuterin, a broad-spectrum antimicrobial compound, and research suggests it may help support gastric motility and reduce visceral discomfort through TRPV1 channel modulation. The DSM 17938 strain has been extensively studied for supporting comfort in colicky infants.

How It Works

Produces reuterin, a broad-spectrum antimicrobial compound (3-hydroxypropionaldehyde); accelerates gastric emptying via enteric nervous system modulation; reduces visceral pain through TRPV1 channel modulation; modulates gut motility and colonic transit.

Evidence For Conditions

Condition	Grade	Studies	Participants
Bloating and Intestinal Gas	B	7	500	View →
Gastroesophageal Reflux Disease (GERD)	C	2	250	View →

Side Effects

Mild gas in initial days of use
Occasional increased fussiness in infants during adjustment (transient)
Rare loose stools
Very rare: bacteremia in immunocompromised individuals

Drug & Supplement Interactions

Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
Immunosuppressants (theoretical risk in immunocompromised patients)
Proton pump inhibitors (altered gastric pH may affect colonization)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Bacillus coagulans Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium lactis Bifidobacterium longum

Quick Facts

Dosage: General: 100 million - 5 billion CFU/day; Infantile_Colic: 100 million CFU/day (DSM 17938 strain, 5 drops); Adult_Gi_Support: 1-5 billion CFU/day
Forms: drops (liquid) chewable tablet capsule powder
Natural Sources: Breast milk, Human GI tract, Sourdough bread, Fermented meats
Upper Limit: Well-tolerated up to 10 billion CFU/day in clinical trials
Best Time: Before meals or on empty stomach; for infants, add drops to breast milk or formula

Evidence Summary

Bloating and Intestinal Gas B

Gastroesophageal Reflux Disease (GERD) C

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.