What is the recommended dosage for Lactobacillus gasseri?

General: 1-10 billion CFU/day; Gerd Support: 1-5 billion CFU/day; H Pylori Support: 100 million CFU/day (LG21 strain, yogurt form) for 8-12 weeks

What are the side effects of Lactobacillus gasseri?

Potential side effects include: Mild gas during initial use, Occasional loose stools, Rare abdominal discomfort, Very rare: bacteremia in immunocompromised individuals.

What is Lactobacillus gasseri and how does it work for gut health?

Lactobacillus gasseri is a probiotic species found naturally in the human gastrointestinal tract and breast milk. It produces bacteriocins (natural antimicrobial compounds) and lactic acid that help inhibit harmful bacteria. Research suggests L. gasseri may support digestive comfort, help reduce abdominal bloating, and has been studied for its potential role in supporting healthy body composition.

What is the recommended dosage of Lactobacillus gasseri?

Clinical studies have used L. gasseri at dosages of 1 billion to 10 billion CFU per day. The strain L. gasseri SBT2055 (LG2055) has been the most extensively studied, typically at approximately 5 billion CFU daily for 12 weeks. Consistent daily intake appears to be important for maintaining benefits.

Are there side effects or interactions with Lactobacillus gasseri?

L. gasseri is generally well-tolerated with minimal reported side effects in clinical trials. As with other probiotic species, mild and temporary digestive symptoms may occur when starting supplementation. No significant drug interactions have been documented. Standard probiotic precautions apply for immunocompromised individuals.

Lactobacillus gasseri

probiotic_strain

Also known as: L. gasseri, LG21, BNR17, Meiji LG21 yogurt

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About

Lactobacillus gasseri is a probiotic species that naturally inhabits the human stomach and intestinal tract. Research suggests the LG21 strain may help support healthy pepsinogen production and gastric function, and has been studied for its potential to suppress H. pylori colonization. It may also help modulate gastric acid secretion, supporting overall upper GI comfort.

How It Works

Increases pepsinogen production accelerating protein digestion; suppresses H. pylori colonization through competitive exclusion and lactic acid production; modulates gastric acid secretion via interaction with parietal cell signaling; promotes healthy gastric mucosal environment.

Evidence For Conditions

Condition	Grade	Studies	Participants
Helicobacter pylori Infection	B	3	350	View →
Gastroesophageal Reflux Disease (GERD)	D	3	300	View →

Side Effects

Mild gas during initial use
Occasional loose stools
Rare abdominal discomfort
Very rare: bacteremia in immunocompromised individuals

Drug & Supplement Interactions

Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
Proton pump inhibitors (altered gastric pH may affect colonization)
Immunosuppressants (theoretical risk in immunocompromised patients)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Bacillus coagulans Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium lactis Bifidobacterium longum

Quick Facts

Dosage: General: 1-10 billion CFU/day; Gerd_Support: 1-5 billion CFU/day; H_Pylori_Support: 100 million CFU/day (LG21 strain, yogurt form) for 8-12 weeks
Forms: capsule yogurt powder tablet
Natural Sources: Human gastric mucosa (commensal), Breast milk, Fermented dairy (LG21 yogurt in Japan)
Upper Limit: Well-tolerated up to 10 billion CFU/day in clinical trials
Best Time: Before meals or with meals; yogurt form taken with food

Evidence Summary

Helicobacter pylori Infection B

Gastroesophageal Reflux Disease (GERD) D

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.