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Expression levels of circadian-clock genes including CLOCK, BMAL1, and PER2 are measured before and after butyrate supplementation. Changes in gene expression suggest butyrate may help regulate disrupted circadian rhythms in IBD.
Figure 2
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Effects of short-chain fatty acid-butyrate supplementation on expression of circadian-clock genes, sleep quality, and inflammation in patients with active ulcerative …Cite This Figure
![Figure 2: Expression levels of circadian-clock genes including CLOCK, BMAL1, and PER2 are measured before and after butyrate supplementation. Changes in gene expression suggest butyrate may help regulate disrupted circadian rhythms in IBD.]() > Source: Donya Firoozi et al. "Effects of short-chain fatty acid-butyrate supplementation on expression of circ." *Lipids in health and disease*, 2024. PMID: [39003477](https://pubmed.ncbi.nlm.nih.gov/39003477/)
<figure> <img src="" alt="Expression levels of circadian-clock genes including CLOCK, BMAL1, and PER2 are measured before and after butyrate supplementation. Changes in gene expression suggest butyrate may help regulate disrupted circadian rhythms in IBD." /> <figcaption>Figure 2. Expression levels of circadian-clock genes including CLOCK, BMAL1, and PER2 are measured before and after butyrate supplementation. Changes in gene expression suggest butyrate may help regulate disrupted circadian rhythms in IBD.<br> Source: Donya Firoozi et al. "Effects of short-chain fatty acid-butyrate supplementation on expression of circ." <em>Lipids in health and disease</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/39003477/">39003477</a></figcaption> </figure>