**Figure 6.** Figure 1. Comparison of mRNA expression of CYP2A5 and CAR in murine liver of GF and SPF mice. Gene expression of (A,C) CYP2A5 and (B,D) constitutive androstane receptor (CAR). Results are expressed relative to SPF healthy control group (CT) and represent means ± SD. Signiﬁcance of differences from the control was determined using one-way analysis of variance (ANOVA) with the Tukey’s multiple post-hoc test being used for comparison of experimental groups to respective SPF and GF controls (*** p < 0.001, ** p < 0.01, * p < 0.05). CT (group 1): drinking water for 1 week; DSS (group 2): 1 week 2.5% DSS in drinking water; SB + DSS (group 3): 0.5% SB in drinking water for 2 weeks followed by a week of 2.5% DSS in drinking water; SB (group 4): 0.5% SB in drinking water for 2 weeks.

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Comparison of mRNA expression of CYP2A5 and CAR in murine liver of GF and SPF mice. Gene expression of (A,C) CYP2A5 and (B,D) constitutive androstane receptor (CAR).

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Statistical analysis from research investigating effect of DSS, comparing treatment groups and control conditions.

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Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5: Contribution of the Microbiome.

International journal of molecular sciences (2022)

PMID: 36232929

DOI: 10.3390/ijms231911627

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![Figure 6: Comparison of mRNA expression of CYP2A5 and CAR in murine liver of GF and SPF mice. Gene expression of (A,C) CYP2A5 and (B,D) constitutive androstane receptor (CAR).](https://pdfs.citedhealth.com/figures/36232929/67.png)

> Source: Stefan Satka et al. "Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5." *International journal of molecular sciences*, 2022. PMID: [36232929](https://pubmed.ncbi.nlm.nih.gov/36232929/)

<figure>
  <img src="https://pdfs.citedhealth.com/figures/36232929/67.png" alt="Comparison of mRNA expression of CYP2A5 and CAR in murine liver of GF and SPF mice. Gene expression of (A,C) CYP2A5 and (B,D) constitutive androstane receptor (CAR)." />
  <figcaption>Figure 6. Comparison of mRNA expression of CYP2A5 and CAR in murine liver of GF and SPF mice. Gene expression of (A,C) CYP2A5 and (B,D) constitutive androstane receptor (CAR).<br>  Source: Stefan Satka et al. "Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5." <em>International journal of molecular sciences</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36232929/">36232929</a></figcaption>
</figure>

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