Lactobacillus reuteri para Gastroesophageal Reflux Disease (GERD)

Q: Does Lactobacillus reuteri help with Gastroesophageal Reflux Disease (GERD)?

Based on 2 studies with 250 participants, there is limited but promising evidence that Lactobacillus reuteri may support Gastroesophageal Reflux Disease (GERD) management. Our evidence grade is C (Some Evidence).

Q: How much Lactobacillus reuteri should I take for Gastroesophageal Reflux Disease (GERD)?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Lactobacillus reuteri and Gastroesophageal Reflux Disease (GERD)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

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Conclusión

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

Key Study Findings

basic science

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.

Dose: Lactobacillus reuteri E9 (dose not specified) vs: Placebo Efecto: None < 0.05

Review

The evidence for probiotics in the treatment of digestive disorders in the pediatric population.

Dose: None vs: None Outcome: None Efecto: None None

Población: Pediatric population

Key Statistics

Estudios

250

Participantes

↑

Positive

Calificación

Referenced Papers

The evidence for probiotics in the treatment of digestive disorders in the pediatric population. Review

Journal of gastroenterology … 2025 10 citas

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA. Other

Frontiers in bioscience … 2025

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:: 100 million - 5 billion CFU/day
infantilecolic:: 100 million CFU/day (DSM 17938 strain, 5 drops)
adultgisupport:: 1-5 billion CFU/day

Límite superior: Well-tolerated up to 10 billion CFU/day in clinical trials

Dosificaciones estudiadas en la investigación

Dosificación	Duración	Efecto	N
Lactobacillus reuteri E9 (dose not specified)	--	Positive	--
None	--	Mixed	--

Mejor momento para tomar: Before meals or on empty stomach; for infants, add drops to breast milk or formula

Safety & Side Effects

Efectos secundarios reportados

⚠ Mild gas in initial days of use
⚠ Occasional increased fussiness in infants during adjustment (transient)
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

Interacciones conocidas

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (theoretical risk in immunocompromised patients)
● Proton pump inhibitors (altered gastric pH may affect colonization)

Ingesta máxima tolerable: Well-tolerated up to 10 billion CFU/day in clinical trials

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Lactobacillus reuteri help with Gastroesophageal Reflux Disease (GERD)?

Based on 2 studies with 250 participants, there is limited but promising evidence that Lactobacillus reuteri may support Gastroesophageal Reflux Disease (GERD) management. Our evidence grade is C (Some Evidence).

How much Lactobacillus reuteri should I take for Gastroesophageal Reflux Disease (GERD)?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lactobacillus reuteri and Gastroesophageal Reflux Disease (GERD)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.

Related Evidence

Otros ingredientes para Gastroesophageal Reflux Disease (GERD)

Lactobacillus gasseri D Ginger D Slippery Elm D

Lactobacillus reuteri para otras condiciones

Bloating and Intestinal Gas B

Veredicto rápido

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

Evidence Strength52%

Moderate confidence

Desglose de estudios

RCT (0)Meta (0)Other (2)

Comparar alternativas

Vea cómo se comparan otros ingredientes para esta condición.

Ver todos los ingredientes para Gastroesophageal Reflux Disease (GERD)

Más información

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.