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Key evidence: Two RCTs that fulfilled inclusion criteria for this consensus, compared polyethylene glycol 3350 (PEG) and placebo in a total of 181 patients with Rome (II or III) diagnosed IBS-C (165, 166). Compared with placebo, there was a statistically
Figure 5. Key evidence: Two RCTs that fulfilled inclusion criteria for this consensus, compared polyethylene glycol 3350 (PEG) and placebo in a total of 181 patients with Rome (II or III) diagnosed IBS-C (165, 166). Compared with placebo, there was a statistically significant increase in the number of bowel movements in one study (166), but not in the other (165), and there was no significant improvement in abdominal pain in either

Beschreibung

Polyethylene glycol 3350 is evaluated for IBS with constipation based on two RCTs totaling 181 patients. Evidence supports its use for improving stool consistency, though effects on abdominal pain are less consistent.

Figure 5

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Source Paper

Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Irritable Bowel Syndrome (IBS).

Journal of the Canadian Association of Gastroenterology (2019)

PMID: 31294724

DOI: 10.1093/jcag/gwy071

Cite This Figure

![Figure 5: Polyethylene glycol 3350 is evaluated for IBS with constipation based on two RCTs totaling 181 patients. Evidence supports its use for improving stool consistency, though effects on abdominal pain are less consistent.](https://pdfs.citedhealth.com/figures/31294724/368.png)

> Source: Paul Moayyedi et al. "Canadian Association of Gastroenterology Clinical Practice Guideline for the Man." *Journal of the Canadian Association of Gastroenterology*, 2019. PMID: [31294724](https://pubmed.ncbi.nlm.nih.gov/31294724/)
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  <img src="https://pdfs.citedhealth.com/figures/31294724/368.png" alt="Polyethylene glycol 3350 is evaluated for IBS with constipation based on two RCTs totaling 181 patients. Evidence supports its use for improving stool consistency, though effects on abdominal pain are less consistent." />
  <figcaption>Figure 5. Polyethylene glycol 3350 is evaluated for IBS with constipation based on two RCTs totaling 181 patients. Evidence supports its use for improving stool consistency, though effects on abdominal pain are less consistent.<br>  Source: Paul Moayyedi et al. "Canadian Association of Gastroenterology Clinical Practice Guideline for the Man." <em>Journal of the Canadian Association of Gastroenterology</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31294724/">31294724</a></figcaption>
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