Lactobacillus reuteri für Gastroesophageal Reflux Disease (GERD)

Q: Does Lactobacillus reuteri help with Gastroesophageal Reflux Disease (GERD)?

Based on 2 studies with 250 participants, there is limited but promising evidence that Lactobacillus reuteri may support Gastroesophageal Reflux Disease (GERD) management. Our evidence grade is C (Some Evidence).

Q: How much Lactobacillus reuteri should I take for Gastroesophageal Reflux Disease (GERD)?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Lactobacillus reuteri and Gastroesophageal Reflux Disease (GERD)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

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Fazit

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

Key Study Findings

basic science

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.

Dose: Lactobacillus reuteri E9 (dose not specified) vs.: Placebo Wirkung: None < 0.05

Review

The evidence for probiotics in the treatment of digestive disorders in the pediatric population.

Dose: None vs.: None Outcome: None Wirkung: None None

Population: Pediatric population

Key Statistics

Studien

250

Teilnehmer

↑

Positive

Bewertung

Referenced Papers

The evidence for probiotics in the treatment of digestive disorders in the pediatric population. Review

Journal of gastroenterology … 2025 10 Zitierungen

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA. Other

Frontiers in bioscience … 2025

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:: 100 million - 5 billion CFU/day
infantilecolic:: 100 million CFU/day (DSM 17938 strain, 5 drops)
adultgisupport:: 1-5 billion CFU/day

Obergrenze: Well-tolerated up to 10 billion CFU/day in clinical trials

In der Forschung untersuchte Dosierungen

Dosierung	Dauer	Wirkung	N
Lactobacillus reuteri E9 (dose not specified)	--	Positive	--
None	--	Mixed	--

Beste Einnahmezeit: Before meals or on empty stomach; for infants, add drops to breast milk or formula

Safety & Side Effects

Gemeldete Nebenwirkungen

⚠ Mild gas in initial days of use
⚠ Occasional increased fussiness in infants during adjustment (transient)
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

Bekannte Wechselwirkungen

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (theoretical risk in immunocompromised patients)
● Proton pump inhibitors (altered gastric pH may affect colonization)

Tolerierbare Höchstaufnahmemenge: Well-tolerated up to 10 billion CFU/day in clinical trials

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Lactobacillus reuteri help with Gastroesophageal Reflux Disease (GERD)?

Based on 2 studies with 250 participants, there is limited but promising evidence that Lactobacillus reuteri may support Gastroesophageal Reflux Disease (GERD) management. Our evidence grade is C (Some Evidence).

How much Lactobacillus reuteri should I take for Gastroesophageal Reflux Disease (GERD)?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lactobacillus reuteri and Gastroesophageal Reflux Disease (GERD)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.

Related Evidence

Andere Inhaltsstoffe für Gastroesophageal Reflux Disease (GERD)

Lactobacillus gasseri D Ginger D Slippery Elm D

Lactobacillus reuteri für andere Beschwerden

Bloating and Intestinal Gas B

Kurzfazit

Limited evidence that L. reuteri improves regurgitation in infants. Adult GERD evidence is weak.

Evidence Strength52%

Moderate confidence

Studienübersicht

RCT (0)Meta (0)Other (2)

Alternativen vergleichen

Sehen Sie, wie andere Inhaltsstoffe bei dieser Beschwerde abschneiden.

Alle Inhaltsstoffe ansehen für Gastroesophageal Reflux Disease (GERD)

Mehr erfahren

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