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Vitamin D is increasingly viewed as an immune modulator capable of directly impacting both innate and adaptive immune responses (Figure 2). Given that almost all immune cells express VDR,2 it is not surprising that vitamin D is closely correlated with imm
Figure 1. Vitamin D is increasingly viewed as an immune modulator capable of directly impacting both innate and adaptive immune responses (Figure 2). Given that almost all immune cells express VDR,2 it is not surprising that vitamin D is closely correlated with immunomodulation and the development of immune-related diseases including IBD.

Mô tả

Vitamin D's multifaceted role as an immune modulator is discussed, noting that nearly all immune cells express the vitamin D receptor and that deficiency is closely correlated with increased susceptibility to immune-mediated diseases.

More Figures from This Paper

Vitamin D impacts on innate and adaptive immunity are illustrated, showing inhibition of LPS-induced p38 activation, suppression of IL-6 and TNF-alpha by monocytes, and downregulation of TLR-9 expression in immune cells.

Figure 2

Vitamin D impacts on innate and adaptive immunity are illustrated, showing inhibition of LPS-induced p38 activation, suppression of IL-6 and TNF-alpha by monocytes, and downregulation of TLR-9 expression in immune cells.

diagram
Vitamin D's influence on inflammatory bowel disease development is depicted through three interconnected pathways: intestinal immune regulation, microbiota composition, and mucosal barrier integrity.

Figure 3

Vitamin D's influence on inflammatory bowel disease development is depicted through three interconnected pathways: intestinal immune regulation, microbiota composition, and mucosal barrier integrity.

diagram

Figure 1

Diagram
720 × 334px · 39,9 KB

Source Paper

The Role of Vitamin D in Immune System and Inflammatory Bowel Disease.

Journal of inflammation research (2022)

PMID: 35662873

DOI: 10.2147/JIR.S363840

Cite This Figure

![Figure 1: Vitamin D's multifaceted role as an immune modulator is discussed, noting that nearly all immune cells express the vitamin D receptor and that deficiency is closely correlated with increased susceptibility to immune-mediated diseases.](https://pdfs.citedhealth.com/figures/35662873/248.png)

> Source: Zengrong Wu et al. "The Role of Vitamin D in Immune System and Inflammatory Bowel Disease.." *Journal of inflammation research*, 2022. PMID: [35662873](https://pubmed.ncbi.nlm.nih.gov/35662873/)
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  <img src="https://pdfs.citedhealth.com/figures/35662873/248.png" alt="Vitamin D's multifaceted role as an immune modulator is discussed, noting that nearly all immune cells express the vitamin D receptor and that deficiency is closely correlated with increased susceptibility to immune-mediated diseases." />
  <figcaption>Figure 1. Vitamin D's multifaceted role as an immune modulator is discussed, noting that nearly all immune cells express the vitamin D receptor and that deficiency is closely correlated with increased susceptibility to immune-mediated diseases.<br>  Source: Zengrong Wu et al. "The Role of Vitamin D in Immune System and Inflammatory Bowel Disease.." <em>Journal of inflammation research</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35662873/">35662873</a></figcaption>
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