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Figure 4

Description

Overall side effect incidence is significantly reduced in patients receiving adjunctive probiotic supplementation during H. pylori eradication therapy. Diarrhea, nausea, and abdominal pain are the adverse events most consistently ameliorated.

More Figures from This Paper

Forest plot of pooled H. pylori eradication rates demonstrates a modest but statistically significant improvement when probiotics are added to standard antibiotic therapy. Effect sizes vary across individual studies depending on probiotic strains used.

Figure 2

Forest plot of pooled H. pylori eradication rates demonstrates a modest but statistically significant improvement when probiotics are added to standard antibiotic therapy. Effect sizes vary across individual studies depending on probiotic strains used.

forest_plot
Subgroup analysis by probiotic species reveals that Lactobacillus-based preparations and multi-strain combinations show the most consistent benefit for improving eradication rates. Single-strain Saccharomyces boulardii also demonstrates efficacy.

Figure 3

Subgroup analysis by probiotic species reveals that Lactobacillus-based preparations and multi-strain combinations show the most consistent benefit for improving eradication rates. Single-strain Saccharomyces boulardii also demonstrates efficacy.

forest_plot
Funnel plot assessment for publication bias in the meta-analysis shows relatively symmetric distribution of studies, suggesting minimal publication bias in the included eradication rate trials.

Figure 5

Funnel plot assessment for publication bias in the meta-analysis shows relatively symmetric distribution of studies, suggesting minimal publication bias in the included eradication rate trials.

chart
Sensitivity analyses confirm the robustness of the pooled treatment effect, with no single study disproportionately influencing the overall result. Risk of bias assessment across included trials indicates moderate quality evidence.

Figure 6

Sensitivity analyses confirm the robustness of the pooled treatment effect, with no single study disproportionately influencing the overall result. Risk of bias assessment across included trials indicates moderate quality evidence.

chart

Figure 4

Forest Plot
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Source Paper

The effect of probiotics supplementation on Helicobacter pylori eradication rates and side effects during eradication therapy: a meta-analysis.

PloS one (2014)

PMID: 25365320

DOI: 10.1371/journal.pone.0111030

Cite This Figure

![Figure 4: Overall side effect incidence is significantly reduced in patients receiving adjunctive probiotic supplementation during H. pylori eradication therapy. Diarrhea, nausea, and abdominal pain are the adverse events most consistently ameliorated.](https://pdfs.citedhealth.com/figures/25365320/852.png)

> Source: Yini Dang et al. "The effect of probiotics supplementation on Helicobacter pylori eradication rate." *PloS one*, 2014. PMID: [25365320](https://pubmed.ncbi.nlm.nih.gov/25365320/)
<figure>
  <img src="https://pdfs.citedhealth.com/figures/25365320/852.png" alt="Overall side effect incidence is significantly reduced in patients receiving adjunctive probiotic supplementation during H. pylori eradication therapy. Diarrhea, nausea, and abdominal pain are the adverse events most consistently ameliorated." />
  <figcaption>Figure 4. Overall side effect incidence is significantly reduced in patients receiving adjunctive probiotic supplementation during H. pylori eradication therapy. Diarrhea, nausea, and abdominal pain are the adverse events most consistently ameliorated.<br>  Source: Yini Dang et al. "The effect of probiotics supplementation on Helicobacter pylori eradication rate." <em>PloS one</em>, 2014. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/25365320/">25365320</a></figcaption>
</figure>

Related Evidence

B
Lactobacillus gasseri for Helicobacter pylori Infection

Grade B · 3 studies

 D
Lactobacillus gasseri for Gastroesophageal Reflux Disease (GERD)

Grade D · 3 studies