Is there a role for fish oil in inflammatory bowel disease?

Affifa Farrukh, John Francis Mayberry

Review World journal of clinical cases 2014 25 trích dẫn

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Loại nghiên cứu: Review
Đối tượng nghiên cứu: Patients with inflammatory bowel disease

Can thiệp: Is there a role for fish oil in inflammatory bowel disease? None
Đối chứng: None
Kết quả chính: Inflammatory bowel disease management
Xu hướng hiệu quả: Mixed
Nguy cơ sai lệch: Unclear

Abstract

A number of animal and human studies suggest omega 3-fatty acids are anti-inflammatory. As a result they may have a therapeutic role in inflammatory bowel disease (IBD). The aim of this review is to briefly assess the literature about the utility of poly-unsaturated fatty acids (PUFAs) in the management of IBD. Taken together, almost all studies suggest some beneficial effects of n-3 PUFAs in IBD but the mechanism remains controversial. In addition, clinical benefit seems to be largely confined to ulcerative colitis. However all studies have concluded that these compounds have no potential for a steroid/aminosalicylic acid sparing effect or to maintain remission. Now the question arises as to whether this treatment is of real value to IBD patients? Clearly they have some therapeutic potential but further work is needed.

Tóm lược

Almost all studies suggest some beneficial effects of n-3 PUFAs in IBD but the mechanism remains controversial and clinical benefit seems to be largely confined to ulcerative colitis.

Used In Evidence Reviews

C Omega-3 Fatty Acids (EPA/DHA) cho Ulcerative Colitis (UC)

Is there a role for fish oil in inflammatory bowel disease?

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Tóm lược

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