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A re-appraisal of lactose intolerance.

L K Harrington, J F Mayberry
Review International journal of clinical practice 2008 60 trích dẫn
PubMed DOI
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Study Design

Loại nghiên cứu
Review
Đối tượng nghiên cứu
A literature review was carried out to meet the aims of this paper
Can thiệp
A re-appraisal of lactose intolerance. None
Đối chứng
None
Kết quả chính
A re-appraisal of lactose intolerance.
Xu hướng hiệu quả
Mixed
Nguy cơ sai lệch
Unclear

Abstract

BACKGROUND: Lactose, beta-galactose-1,4-glucose, is hydrolysed by the enzyme lactase. Lactose intolerance occurs when lactase deficiency causes clinical symptoms. AIMS: To provide an overview of lactose intolerance, including definition, aetiology and epidemiology, the clinical symptoms and diagnostic testing and management. METHODS: A literature review was carried out to meet the aims of this paper. This resulted in the analysis of a database of patients tested for lactose intolerance to provide examples of the consequences of problems of terminology identified. CONCLUSIONS: The terminology relating to lactose intolerance is confusing for clinicians and researchers. Clinicians need to ensure that these problematic terms do not cause diagnostic mistakes and inappropriate treatment. Researchers should be aware of inconsistent terminology in studies and resultant problems with the interpretation of results.

Tóm lược

The objective of this study was to establish whether or not the presence of lactose intolerance in the absence of lactase deficiency in mice is a cause for concern or simply a coincidence.

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