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Mediation analysis diagram illustrating the potential pathway through which total omega-3 fatty acids may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.
Figure 241
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Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bowel Disease via Circulating Metabolites: A Mediation Mendelian Randomization Study.Cite This Figure
![Figure 241: Mediation analysis diagram illustrating the potential pathway through which total omega-3 fatty acids may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.]() > Source: Xiaojing Jia et al. "Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bo." *Metabolites*, 2023. PMID: [37887366](https://pubmed.ncbi.nlm.nih.gov/37887366/)
<figure> <img src="" alt="Mediation analysis diagram illustrating the potential pathway through which total omega-3 fatty acids may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association." /> <figcaption>Figure 241. Mediation analysis diagram illustrating the potential pathway through which total omega-3 fatty acids may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.<br> Source: Xiaojing Jia et al. "Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bo." <em>Metabolites</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/37887366/">37887366</a></figcaption> </figure>