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Correlation analysis between gut microbiota composition and hepatic lipid parameters links specific bacterial taxa to the amelioration of non-alcoholic fatty liver disease.

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The experimental design outlines the group allocation including sodium carboxymethyl cellulose control, berberine-evodiamine combination, and fenofibrate positive control arms.

Figure 5

The experimental design outlines the group allocation including sodium carboxymethyl cellulose control, berberine-evodiamine combination, and fenofibrate positive control arms.

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Gut microbiota composition analyzed by 16S rRNA sequencing reveals distinct community structures across treatment groups, with the combination therapy restoring microbial diversity.

Figure 6

Gut microbiota composition analyzed by 16S rRNA sequencing reveals distinct community structures across treatment groups, with the combination therapy restoring microbial diversity.

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Alpha diversity indices of gut microbiota are compared across groups, indicating that berberine and evodiamine co-administration partially reverses high-fat diet-induced dysbiosis.

Figure 7

Alpha diversity indices of gut microbiota are compared across groups, indicating that berberine and evodiamine co-administration partially reverses high-fat diet-induced dysbiosis.

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Key bacterial taxa differentially abundant between treatment groups are identified, with specific genera associated with improved metabolic outcomes in the combination therapy arm.

Figure 8

Key bacterial taxa differentially abundant between treatment groups are identified, with specific genera associated with improved metabolic outcomes in the combination therapy arm.

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Short-chain fatty acid concentrations in fecal samples reflect changes in microbial metabolic activity following berberine and evodiamine treatment.

Figure 9

Short-chain fatty acid concentrations in fecal samples reflect changes in microbial metabolic activity following berberine and evodiamine treatment.

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Figure 10

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Source Paper

The combination of berberine and evodiamine ameliorates high-fat diet-induced non-alcoholic fatty liver disease associated with modulation of gut microbiota in …

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas (2022)

PMID: 35584453

DOI: 10.1590/1414-431X2022e12096

Cite This Figure

![Figure 10: Correlation analysis between gut microbiota composition and hepatic lipid parameters links specific bacterial taxa to the amelioration of non-alcoholic fatty liver disease.](https://pdfs.citedhealth.com/figures/35584453/170.png)

> Source: Yufan Dai et al. "The combination of berberine and evodiamine ameliorates high-fat diet-induced no." *Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas*, 2022. PMID: [35584453](https://pubmed.ncbi.nlm.nih.gov/35584453/)
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  <img src="https://pdfs.citedhealth.com/figures/35584453/170.png" alt="Correlation analysis between gut microbiota composition and hepatic lipid parameters links specific bacterial taxa to the amelioration of non-alcoholic fatty liver disease." />
  <figcaption>Figure 10. Correlation analysis between gut microbiota composition and hepatic lipid parameters links specific bacterial taxa to the amelioration of non-alcoholic fatty liver disease.<br>  Source: Yufan Dai et al. "The combination of berberine and evodiamine ameliorates high-fat diet-induced no." <em>Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35584453/">35584453</a></figcaption>
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