Figure 421

![Figure 421: Mediation analysis diagram illustrating the potential pathway through which docosahexaenoic acid (DHA) may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.]()

> Source: Xiaojing Jia et al. "Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bo." *Metabolites*, 2023. PMID: [37887366](https://pubmed.ncbi.nlm.nih.gov/37887366/)

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  <img src="" alt="Mediation analysis diagram illustrating the potential pathway through which docosahexaenoic acid (DHA) may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association." />
  <figcaption>Figure 421. Mediation analysis diagram illustrating the potential pathway through which docosahexaenoic acid (DHA) may influence Crohn's disease (CD) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.<br>  Source: Xiaojing Jia et al. "Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bo." <em>Metabolites</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/37887366/">37887366</a></figcaption>
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