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The experimental design outlines the group allocation including sodium carboxymethyl cellulose control, berberine-evodiamine combination, and fenofibrate positive control arms.
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Figure 6
Gut microbiota composition analyzed by 16S rRNA sequencing reveals distinct community structures across treatment groups, with the combination therapy restoring microbial diversity.
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Figure 7
Alpha diversity indices of gut microbiota are compared across groups, indicating that berberine and evodiamine co-administration partially reverses high-fat diet-induced dysbiosis.
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Figure 8
Key bacterial taxa differentially abundant between treatment groups are identified, with specific genera associated with improved metabolic outcomes in the combination therapy arm.
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Figure 9
Short-chain fatty acid concentrations in fecal samples reflect changes in microbial metabolic activity following berberine and evodiamine treatment.
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Figure 10
Correlation analysis between gut microbiota composition and hepatic lipid parameters links specific bacterial taxa to the amelioration of non-alcoholic fatty liver disease.
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FlowchartSource Paper
The combination of berberine and evodiamine ameliorates high-fat diet-induced non-alcoholic fatty liver disease associated with modulation of gut microbiota in …Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas (2022)
PMID: 35584453
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 > Source: Yufan Dai et al. "The combination of berberine and evodiamine ameliorates high-fat diet-induced no." *Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas*, 2022. PMID: [35584453](https://pubmed.ncbi.nlm.nih.gov/35584453/)
<figure> <img src="https://pdfs.citedhealth.com/figures/35584453/95.png" alt="The experimental design outlines the group allocation including sodium carboxymethyl cellulose control, berberine-evodiamine combination, and fenofibrate positive control arms." /> <figcaption>Figure 5. The experimental design outlines the group allocation including sodium carboxymethyl cellulose control, berberine-evodiamine combination, and fenofibrate positive control arms.<br> Source: Yufan Dai et al. "The combination of berberine and evodiamine ameliorates high-fat diet-induced no." <em>Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35584453/">35584453</a></figcaption> </figure>