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Funnel plot assessment for publication bias in the meta-analysis shows relatively symmetric distribution of studies, suggesting minimal publication bias in the included eradication rate trials.
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Figure 2
Forest plot of pooled H. pylori eradication rates demonstrates a modest but statistically significant improvement when probiotics are added to standard antibiotic therapy. Effect sizes vary across individual studies depending on probiotic strains used.
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Figure 3
Subgroup analysis by probiotic species reveals that Lactobacillus-based preparations and multi-strain combinations show the most consistent benefit for improving eradication rates. Single-strain Saccharomyces boulardii also demonstrates efficacy.
forest_plot
Figure 4
Overall side effect incidence is significantly reduced in patients receiving adjunctive probiotic supplementation during H. pylori eradication therapy. Diarrhea, nausea, and abdominal pain are the adverse events most consistently ameliorated.
forest_plot
Figure 6
Sensitivity analyses confirm the robustness of the pooled treatment effect, with no single study disproportionately influencing the overall result. Risk of bias assessment across included trials indicates moderate quality evidence.
chartFigure 5
ChartSource Paper
The effect of probiotics supplementation on Helicobacter pylori eradication rates and side effects during eradication therapy: a meta-analysis.Cite This Figure
 > Source: Yini Dang et al. "The effect of probiotics supplementation on Helicobacter pylori eradication rate." *PloS one*, 2014. PMID: [25365320](https://pubmed.ncbi.nlm.nih.gov/25365320/)
<figure> <img src="https://pdfs.citedhealth.com/figures/25365320/865.png" alt="Funnel plot assessment for publication bias in the meta-analysis shows relatively symmetric distribution of studies, suggesting minimal publication bias in the included eradication rate trials." /> <figcaption>Figure 5. Funnel plot assessment for publication bias in the meta-analysis shows relatively symmetric distribution of studies, suggesting minimal publication bias in the included eradication rate trials.<br> Source: Yini Dang et al. "The effect of probiotics supplementation on Helicobacter pylori eradication rate." <em>PloS one</em>, 2014. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/25365320/">25365320</a></figcaption> </figure>