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Lactose intolerance: myths and facts. An update.

M Del Carmen Toca, Adriana Fernández, Marina Orsi, Omar Tabacco, Gabriel Vinderola
Review Archivos argentinos de pediatria 2022 42 citações
PubMed DOI
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Study Design

Tipo de Estudo
Review
População
Lactose intolerant individuals
Intervenção
Lactose intolerance: myths and facts. An update. None
Comparador
None
Desfecho Primário
Lactose digestion and tolerance management
Direção do Efeito
Neutral
Risco de Viés
Unclear

Abstract

Lactose is the main carbohydrate present in human milk. It is a disaccharide made up of glucose and galactose. It is produced in the mammary glands, regardless of maternal diet. In addition to providing energy, it is the only source of dietary galactose, necessary for macromolecule synthesis, including oligosaccharides, glycoproteins, and glycolipids. It favors calcium, magnesium, and zinc absorption and retention. Its digestion by lactase and subsequent absorption occurs in the small intestine. Lactase deficiency may be classified into congenital primary (very rare), late-onset primary or secondary due to an injury of the intestine; it may cause intolerance with pain, abdominal distension, abdominal gas, and diarrhea. In the colon, it may be hydrolyzed by bifidobacteria and lactobacilli. The nutritional management of intolerance should always preserve breastfeeding. Lactose reduction or elimination should be transient, and eliminated food should be replaced with other similar in calorie, protein, mineral, and vitamin content.

Resumo Rápido

Lactose is the main carbohydrate present in human milk and it is the only source of dietary galactose, necessary for macromolecule synthesis, including oligosaccharides, glycoproteins, and glycolipids.

Used In Evidence Reviews

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