Role of Vitamin D in Inflammatory Bowel Disease.
Study Design
- Study Type
- Review
- Population
- Inflammatory bowel disease patients
- Intervention
- Role of Vitamin D in Inflammatory Bowel Disease. None
- Comparator
- None
- Primary Outcome
- None
- Effect Direction
- Mixed
- Risk of Bias
- Unclear
Abstract
Vitamin D is a secosteroid hormone that possesses immunomodulatory properties and has been demonstrated to potentially influence inflammatory bowel disease (IBD) pathogenesis and activity. Epidemiologic data have associated vitamin D deficiency with an increased risk of IBD, hospitalizations, surgery, and loss of response to biologic therapy. Conversely, IBD itself can lead to vitamin D deficiency. This bidirectional relationship between vitamin D and IBD suggests the need for monitoring and repletion of vitamin D, as needed, in the IBD patient. This review discusses the role of vitamin D in IBD and provides practical guidance on vitamin D repletion.
TL;DR
The bidirectional relationship between vitamin D and IBD suggests the need for monitoring and repletion of vitamin D, as needed, in the IBD patient, and practical guidance on vitamin D repletions is provided.
Used In Evidence Reviews
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