Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome.

Edoardo G Giannini, Carlo Mansi, Pietro Dulbecco, Vincenzo Savarino

Review Nutrition (Burbank, Los Angeles County, Calif.) 2006 119 citations

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Study Design

Study Type: Review
Population: None

Intervention: Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome. None
Comparator: None
Primary Outcome: Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndro
Effect Direction: Positive
Risk of Bias: Unclear

Abstract

Irritable bowel syndrome (IBS) is the world's most common gastrointestinal functional disorder and is associated with several social and economic costs. Health-related quality of life is often impaired in patients with IBS. The pathophysiologic mechanisms underlying IBS remain poorly defined. The therapeutic approach to patients with IBS is based on symptoms, and fibers may play an important role in treatment. Among the various types of fiber, water-soluble, non-gelling fibers seem to be a promising option for treatment of IBS. Partially hydrolyzed guar gum (PHGG) is a water-soluble, non-gelling fiber that has provided therapeutic benefits. In clinical trials, PHGG decreased symptoms in constipation-predominant and diarrhea-predominant forms of IBS and decreased abdominal pain. Further, an improvement in quality of life was observed in patients with IBS during and after treatment with PHGG. Moreover, PHGG seems to have prebiotic properties because it increases the colonic contents of short-chain fatty acids, Lactobacilli, and Bifidobacteria.

TL;DR

Partially hydrolyzed guar gum (PHGG) is a water-soluble, non-gelling fiber that has provided therapeutic benefits in clinical trials and seems to have prebiotic properties because it increases the colonic contents of short-chain fatty acids, Lactobacilli, and Bifidobacteria.

Used In Evidence Reviews

B Partially Hydrolyzed Guar Gum (PHGG) for Irritable Bowel Syndrome (IBS)

Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome.

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Study Design

Abstract

TL;DR

Used In Evidence Reviews

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