Mechanisms of disease: vitamin D and inflammatory bowel disease.

Wee-Chian Lim, Stephen B Hanauer, Yan Chun Li

Review Nature clinical practice. Gastroenterology & hepatology 2005 191 citations

<\/script>\n

`; }, get iframeSnippet() { const domain = 'gutcited.com'; const params = 'pmid\u003D16265284'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Study Design

Study Type: Review
Population: IBD patients

Intervention: Mechanisms of disease: vitamin D and inflammatory bowel disease. Vitamin D
Comparator: None
Primary Outcome: None
Effect Direction: Mixed
Risk of Bias: Unclear

Abstract

Until recently, 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3))-the active form of vitamin D-was thought to function primarily as a regulator of calcium and phosphate metabolism. More diverse functionality was indicated by the discovery of the vitamin D receptor in tissues that are not involved in calcium and phosphate homeostasis. Detection of the vitamin D receptor in monocytes and activated T cells has sparked interest in the immunomodulatory properties of vitamin D. Here, we review the role of vitamin D in regulation of the immune system, and evidence for its involvement in the pathogenesis of inflammatory bowel disease.

TL;DR

The role of vitamin D in regulation of the immune system, and evidence for its involvement in the pathogenesis of inflammatory bowel disease are reviewed.

Used In Evidence Reviews

B Vitamin D for Inflammatory Bowel Disease (IBD) — General

Mechanisms of disease: vitamin D and inflammatory bowel disease.

Embed This Widget

Study Design

Abstract

TL;DR

Used In Evidence Reviews

Similar Papers

Vitamin D and inflammatory diseases.

Diet as a Trigger or Therapy for Inflammatory Bowel Diseases.

Gut-brain Axis and migraine headache: a comprehensive review.

Vitamin D and inflammation.

A double-blind, randomized, placebo-controlled trial of Lactobacillus helveticus and Bifidobacterium longum for the symptoms of depression.

Diet and nutritional factors in inflammatory bowel diseases.