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Deglycyrrhizinated Licorice (DGL)
Deglycyrrhizinated Licorice (DGL)

herb

別名: DGL, Deglycyrrhizinated Glycyrrhiza glabra, GutGard, DGL Licorice

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About

Deglycyrrhizinated licorice (DGL) is a specially processed form of licorice root with the glycyrrhizin compound removed to prevent aldosterone-like side effects (hypertension, hypokalemia). DGL may help stimulate mucus and bicarbonate secretion in the gastric lining and enhance prostaglandin E2 production, which supports mucosal integrity. Research suggests it may support digestive comfort in functional dyspepsia and provide protective support for the gastric lining.

How It Works

Stimulates mucus and bicarbonate secretion in the gastric lining strengthening the mucosal defense barrier; enhances prostaglandin E2 production protecting mucosal integrity; promotes epithelial cell proliferation supporting mucosal repair; glycyrrhizin removed to prevent mineralocorticoid side effects.

Evidence For Conditions

症状・状態 グレード 研究数 参加者数
Functional Dyspepsia C 3 200 詳細を見る →
Peptic Ulcer Disease C 2 150 詳細を見る →

Side Effects

  • Generally very well-tolerated (glycyrrhizin removal reduces risk of major side effects)
  • Mild nausea in rare cases
  • Headache (uncommon)
  • If glycyrrhizin is NOT fully removed: hypertension, hypokalemia, edema (ensure true DGL product)

Drug & Supplement Interactions

  • Digoxin (if residual glycyrrhizin present, hypokalemia may increase digoxin toxicity)
  • Diuretics (if residual glycyrrhizin, additive potassium loss)
  • Corticosteroids (if residual glycyrrhizin, additive mineralocorticoid effects)
  • Warfarin (theoretical interaction if residual glycyrrhizin affects metabolism)

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Related Ingredients

FDAに関する免責事項: これらの記述は米国食品医薬品局(FDA)による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。