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Genetic mechanisms underlying lactose persistence versus non-persistence, illustrating how transcription factors such as CDX-2, HNF1-alpha, and OCT-1 interact with the LCT promoter to regulate lactase gene expression.

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![Figure 7: Genetic mechanisms underlying lactose persistence versus non-persistence, illustrating how transcription factors such as CDX-2, HNF1-alpha, and OCT-1 interact with the LCT promoter to regulate lactase gene expression.]()

> Source: Augusto Anguita-Ruiz et al. "Genetics of Lactose Intolerance: An Updated Review and Online Interactive World ." *Nutrients*, 2020. PMID: [32899182](https://pubmed.ncbi.nlm.nih.gov/32899182/)
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  <img src="" alt="Genetic mechanisms underlying lactose persistence versus non-persistence, illustrating how transcription factors such as CDX-2, HNF1-alpha, and OCT-1 interact with the LCT promoter to regulate lactase gene expression." />
  <figcaption>Figure 7. Genetic mechanisms underlying lactose persistence versus non-persistence, illustrating how transcription factors such as CDX-2, HNF1-alpha, and OCT-1 interact with the LCT promoter to regulate lactase gene expression.<br>  Source: Augusto Anguita-Ruiz et al. "Genetics of Lactose Intolerance: An Updated Review and Online Interactive World ." <em>Nutrients</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32899182/">32899182</a></figcaption>
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