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CONSORT flow diagram for the randomized double-blind trial of Bacillus coagulans Unique IS2 in adult IBS patients shows enrollment of 153 patients, a 2-week placebo run-in, and randomization of 136 compliant participants.

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![Figure 1: CONSORT flow diagram for the randomized double-blind trial of Bacillus coagulans Unique IS2 in adult IBS patients shows enrollment of 153 patients, a 2-week placebo run-in, and randomization of 136 compliant participants.]()

> Source: Ratna Sudha Madempudi et al. "Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2." *Scientific reports*, 2019. PMID: [31434935](https://pubmed.ncbi.nlm.nih.gov/31434935/)
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  <img src="" alt="CONSORT flow diagram for the randomized double-blind trial of Bacillus coagulans Unique IS2 in adult IBS patients shows enrollment of 153 patients, a 2-week placebo run-in, and randomization of 136 compliant participants." />
  <figcaption>Figure 1. CONSORT flow diagram for the randomized double-blind trial of Bacillus coagulans Unique IS2 in adult IBS patients shows enrollment of 153 patients, a 2-week placebo run-in, and randomization of 136 compliant participants.<br>  Source: Ratna Sudha Madempudi et al. "Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2." <em>Scientific reports</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31434935/">31434935</a></figcaption>
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