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Figure 1. Map of the lactase (LCT) and minichromosome maintenance 6 (MCM6) gene region and location of genotyped single nucleotide polymorphisms (SNPs). (a) Distribution of 123 SNPs included in genotype analysis; (b) map of the LCT and MCM6 gene region; (
Figure 1. Figure 1. Map of the lactase (LCT) and minichromosome maintenance 6 (MCM6) gene region and location of genotyped single nucleotide polymorphisms (SNPs). (a) Distribution of 123 SNPs included in genotype analysis; (b) map of the LCT and MCM6 gene region; (c) map of the MCM6 gene; and (d) location of lactase persistence-associated SNPs within introns 9 and 13 of the MCM6 gene in African and European populations [12].

Descrizione

Genetic map of the lactase (LCT) and MCM6 gene region displays the locations of key single nucleotide polymorphisms associated with lactase persistence and non-persistence phenotypes across populations.

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Small bowel water content and breath hydrogen concentrations after consuming glucose and fructose drinks are plotted over time, providing reference data for comparison with lactose challenge tests.

Figure 2

Small bowel water content and breath hydrogen concentrations after consuming glucose and fructose drinks are plotted over time, providing reference data for comparison with lactose challenge tests.

chart
Prevalence of lactose malabsorption versus symptomatic lactose intolerance in IBS-D patients is compared, demonstrating that malabsorption does not invariably produce clinical symptoms.

Figure 3

Prevalence of lactose malabsorption versus symptomatic lactose intolerance in IBS-D patients is compared, demonstrating that malabsorption does not invariably produce clinical symptoms.

chart
Representative photomicrographs of tryptase-positive mast cells in colonic mucosa compare healthy controls with IBS-D patients, suggesting mast cell involvement in lactose intolerance symptomatology.

Figure 4

Representative photomicrographs of tryptase-positive mast cells in colonic mucosa compare healthy controls with IBS-D patients, suggesting mast cell involvement in lactose intolerance symptomatology.

micrograph
Dietary management strategies for lactose intolerance are summarized, including enzyme supplementation, dairy product selection, and gradual tolerance-building approaches.

Figure 5

Dietary management strategies for lactose intolerance are summarized, including enzyme supplementation, dairy product selection, and gradual tolerance-building approaches.

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Figure 1

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Source Paper

Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.

Nutrients (2015)

PMID: 26393648

DOI: 10.3390/nu7095380

Cite This Figure

![Figure 1: Genetic map of the lactase (LCT) and MCM6 gene region displays the locations of key single nucleotide polymorphisms associated with lactase persistence and non-persistence phenotypes across populations.](https://pdfs.citedhealth.com/figures/26393648/61.png)

> Source: Yanyong Deng et al. "Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.." *Nutrients*, 2015. PMID: [26393648](https://pubmed.ncbi.nlm.nih.gov/26393648/)
<figure>
  <img src="https://pdfs.citedhealth.com/figures/26393648/61.png" alt="Genetic map of the lactase (LCT) and MCM6 gene region displays the locations of key single nucleotide polymorphisms associated with lactase persistence and non-persistence phenotypes across populations." />
  <figcaption>Figure 1. Genetic map of the lactase (LCT) and MCM6 gene region displays the locations of key single nucleotide polymorphisms associated with lactase persistence and non-persistence phenotypes across populations.<br>  Source: Yanyong Deng et al. "Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.." <em>Nutrients</em>, 2015. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/26393648/">26393648</a></figcaption>
</figure>

Evidenze correlate

A
Lactase per Lactose Intolerance

Grado A · 15 studi