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Schematic diagram of the JAK/STAT signaling pathway and its role in ulcerative colitis pathogenesis, highlighting intervention points targeted by various natural products. The pathway regulates intestinal inflammation, mucosal barrier integrity, and immune cell differentiation.

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![Figure 1: Schematic diagram of the JAK/STAT signaling pathway and its role in ulcerative colitis pathogenesis, highlighting intervention points targeted by various natural products. The pathway regulates intestinal inflammation, mucosal barrier integrity, and immune cell differentiation.]()

> Source: Dan Long et al. "Natural products for the treatment of ulcerative colitis: focus on the JAK/STAT ." *Frontiers in immunology*, 2025. PMID: [40078988](https://pubmed.ncbi.nlm.nih.gov/40078988/)
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  <img src="" alt="Schematic diagram of the JAK/STAT signaling pathway and its role in ulcerative colitis pathogenesis, highlighting intervention points targeted by various natural products. The pathway regulates intestinal inflammation, mucosal barrier integrity, and immune cell differentiation." />
  <figcaption>Figure 1. Schematic diagram of the JAK/STAT signaling pathway and its role in ulcerative colitis pathogenesis, highlighting intervention points targeted by various natural products. The pathway regulates intestinal inflammation, mucosal barrier integrity, and immune cell differentiation.<br>  Source: Dan Long et al. "Natural products for the treatment of ulcerative colitis: focus on the JAK/STAT ." <em>Frontiers in immunology</em>, 2025. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/40078988/">40078988</a></figcaption>
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