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Bacillus coagulans and its applications in medicine.

Y Mu, Y Cong
Other Beneficial microbes 2019 29 citations
PubMed DOI
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Study Design

Type d'étude
Review
Population
None
Intervention
Bacillus coagulans and its applications in medicine. None
Comparateur
None
Critère de jugement principal
Diarrhea outcomes
Direction de l'effet
Neutral
Risque de biais
Unclear

Abstract

Bacillus coagulans is a probiotic bacterium that produces spores. Due to its excellent stability, it has been widely used in medicine, food and chemical industry. Recent studies have shown that B. coagulans has therapeutic effects on intestinal diseases, such as acute diarrhoea, irritable bowel syndrome, antibiotic-related diarrhoea, constipation and colitis via modulation of the microbiota composition, host immunity and metabolism. Additionally, toxicological experiments and a large number of clinical observations have showed that B. coagulans is safe and has no effect of mutagenicity, teratogenicity or genotoxicity. This review summarises the latest advances associated with B. coagulans, from its biological features, probable action mechanisms, toxicity, and medical applications.

En bref

This review summarises the latest advances associated with B. coagulans, from its biological features, probable action mechanisms, toxicity, and medical applications.

Used In Evidence Reviews

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