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Study enrollment and participant flow through the randomized double-blind trial comparing xylo-oligosaccharides and fructo-oligosaccharides for functional constipation are outlined. The trial design evaluates prebiotic supplementation effects on gut microbiota composition and constipation symptoms.

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![Figure 1: Study enrollment and participant flow through the randomized double-blind trial comparing xylo-oligosaccharides and fructo-oligosaccharides for functional constipation are outlined. The trial design evaluates prebiotic supplementation effects on gut microbiota composition and constipation symptoms.]()

> Source: Wanya Yi et al. "Xylo-oligosaccharides improve functional constipation by targeted enrichment of ." *Food science & nutrition*, 2024. PMID: [38370040](https://pubmed.ncbi.nlm.nih.gov/38370040/)
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  <img src="" alt="Study enrollment and participant flow through the randomized double-blind trial comparing xylo-oligosaccharides and fructo-oligosaccharides for functional constipation are outlined. The trial design evaluates prebiotic supplementation effects on gut microbiota composition and constipation symptoms." />
  <figcaption>Figure 1. Study enrollment and participant flow through the randomized double-blind trial comparing xylo-oligosaccharides and fructo-oligosaccharides for functional constipation are outlined. The trial design evaluates prebiotic supplementation effects on gut microbiota composition and constipation symptoms.<br>  Source: Wanya Yi et al. "Xylo-oligosaccharides improve functional constipation by targeted enrichment of ." <em>Food science & nutrition</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38370040/">38370040</a></figcaption>
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