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Final outcome data from the exploratory IBS trial summarize the overall impact of the probiotic combination on symptom-psychology interactions. Biomarker trajectories suggest a bidirectional relationship between gut and brain responses.

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![Figure 7: Final outcome data from the exploratory IBS trial summarize the overall impact of the probiotic combination on symptom-psychology interactions. Biomarker trajectories suggest a bidirectional relationship between gut and brain responses.]()

> Source: David Groeger et al. "Interactions between symptoms and psychological status in irritable bowel syndro." *Neurogastroenterology and motility*, 2023. PMID: [36178333](https://pubmed.ncbi.nlm.nih.gov/36178333/)
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  <img src="" alt="Final outcome data from the exploratory IBS trial summarize the overall impact of the probiotic combination on symptom-psychology interactions. Biomarker trajectories suggest a bidirectional relationship between gut and brain responses." />
  <figcaption>Figure 7. Final outcome data from the exploratory IBS trial summarize the overall impact of the probiotic combination on symptom-psychology interactions. Biomarker trajectories suggest a bidirectional relationship between gut and brain responses.<br>  Source: David Groeger et al. "Interactions between symptoms and psychological status in irritable bowel syndro." <em>Neurogastroenterology and motility</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36178333/">36178333</a></figcaption>
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