Lactase for Lactose Intolerance
AExogenous lactase enzyme (6,000-9,000 FCC units with dairy) effectively hydrolyzes lactose, reducing symptoms (gas, bloating, diarrhea) by 70-80% in lactase-deficient individuals.
The Bottom Line
Exogenous lactase enzyme (6,000-9,000 FCC units with dairy) effectively hydrolyzes lactose, reducing symptoms (gas, bloating, diarrhea) by 70-80% in lactase-deficient individuals.
Key Study Findings
Population: adults with lactose intolerance
Population: Infants with adverse reactions to cow's milk
Population: None
Population: None
Population: Infants <6 months with colic
Population: Older adults
Key Statistics
15
Studies
1200
Participants
Positive
Grade
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Commonly Used Dosages
- general:
- 3,000-9,000 FCC lactase units per dairy serving
- severeintolerance:
- 9,000-12,000 FCC units per dairy serving
- moderateintolerance:
- 6,000-9,000 FCC units immediately before dairy consumption
Upper limit: No established upper limit; dosage adjusted per dairy serving
Dosages Studied in Research
| Dosage | Duration | Effect | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| Lactase supplementation | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Mixed | -- |
Best taken: Immediately before or with the first bite of dairy-containing food
Safety & Side Effects
Reported Side Effects
- ⚠ Generally very well-tolerated with minimal side effects
- ⚠ Rare allergic reactions to fungal-derived enzyme (Aspergillus source)
- ⚠ Mild abdominal discomfort in rare cases
Known Interactions
- ● No significant drug interactions known
- ● Calcium supplements (lactase does not affect calcium absorption from dairy)
Tolerable upper intake: No established upper limit; dosage adjusted per dairy serving
Always consult your healthcare provider before starting any supplement.
Frequently Asked Questions
Does Lactase help with Lactose Intolerance?
How much Lactase should I take for Lactose Intolerance?
Are there side effects of Lactase?
How strong is the evidence for Lactase and Lactose Intolerance?
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.