Is there a role for fish oil in inflammatory bowel disease?

Affifa Farrukh, John Francis Mayberry

Review World journal of clinical cases 2014 25 citas

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Study Design

Tipo de estudio: Review
Población: Patients with inflammatory bowel disease

Intervención: Is there a role for fish oil in inflammatory bowel disease? None
Comparador: None
Resultado primario: Inflammatory bowel disease management
Dirección del efecto: Mixed
Riesgo de sesgo: Unclear

Abstract

A number of animal and human studies suggest omega 3-fatty acids are anti-inflammatory. As a result they may have a therapeutic role in inflammatory bowel disease (IBD). The aim of this review is to briefly assess the literature about the utility of poly-unsaturated fatty acids (PUFAs) in the management of IBD. Taken together, almost all studies suggest some beneficial effects of n-3 PUFAs in IBD but the mechanism remains controversial. In addition, clinical benefit seems to be largely confined to ulcerative colitis. However all studies have concluded that these compounds have no potential for a steroid/aminosalicylic acid sparing effect or to maintain remission. Now the question arises as to whether this treatment is of real value to IBD patients? Clearly they have some therapeutic potential but further work is needed.

TL;DR

Almost all studies suggest some beneficial effects of n-3 PUFAs in IBD but the mechanism remains controversial and clinical benefit seems to be largely confined to ulcerative colitis.

Used In Evidence Reviews

C Omega-3 Fatty Acids (EPA/DHA) para Ulcerative Colitis (UC)

Is there a role for fish oil in inflammatory bowel disease?

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Study Design

Abstract

TL;DR

Used In Evidence Reviews

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