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Per-protocol analysis of probiotic efficacy in IBS confirms the intent-to-treat findings. Treatment effect magnitudes are slightly larger when only compliant participants are included.

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![Figure 20: Per-protocol analysis of probiotic efficacy in IBS confirms the intent-to-treat findings. Treatment effect magnitudes are slightly larger when only compliant participants are included.]()

> Source: Konstantinos Leventogiannis et al. "Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritabl." *Probiotics and antimicrobial proteins*, 2019. PMID: [29508268](https://pubmed.ncbi.nlm.nih.gov/29508268/)
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  <img src="" alt="Per-protocol analysis of probiotic efficacy in IBS confirms the intent-to-treat findings. Treatment effect magnitudes are slightly larger when only compliant participants are included." />
  <figcaption>Figure 20. Per-protocol analysis of probiotic efficacy in IBS confirms the intent-to-treat findings. Treatment effect magnitudes are slightly larger when only compliant participants are included.<br>  Source: Konstantinos Leventogiannis et al. "Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritabl." <em>Probiotics and antimicrobial proteins</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29508268/">29508268</a></figcaption>
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